GynecologyGynecology2079-56962079-5831Consilium Medicum10626910.26442/20795696.2023.1.202070Review ArticleHuman papillomavirus: etiology, pathogenesis, role, and importance in the development of cervical cancer: A reviewZiganshinAydar M.<p>D. Sci. (Med.)</p>zigaidar@yandex.ruhttps://orcid.org/0000-0001-5474-1080KeidarSergej V.<p>Department Head</p>sergeyke@wmc.gov.ilKhalitovaRegina Sh.<p>Graduate Student</p>regina_badranova@mail.ruhttps://orcid.org/0000-0002-2629-2051MulyukovAirat R.<p>Student</p>mulykov.165@icloud.comhttps://orcid.org/0000-0001-7490-3710Muhamed'yarovaEmiliya N.<p>Student</p>emiemi12@yandex.ruhttps://orcid.org/0000-0002-5004-9393Bashkir State Medical UniversityEdith Wolfson Medical Center2704202325117211404202219082022Copyright © 2023, Consilium Medicum2023<p>Human papillomavirus (HPV) is now considered the most common sexually transmitted infection. Since the discovery by Nobel laureate Harald zur Hausen (2008) of HPV as a virus with a high carcinogenic risk, the strategy for screening and prevention of this disease has changed dramatically. It has significantly increased the relevance of the study of this infection. Although HPV is not life-threatening, its highly oncogenic subtypes can lead to the development of cervical cancer with high mortality.</p>human papillomaviruscervical cancercervical intraepithelial neoplasiaCervarixGardasilGardasil 9вирус папилломы человекарак шейки маткивакцинацияиммунизациядисплазияГардасилЦерварикс[Saslow D, Andrews KS, Manassaram-Baptiste D, et al. American Cancer Society Guideline Development Group. Human papillomavirus vaccination guideline update: American Cancer Society guideline endorsement. CA Cancer J Clin. 2016;66(5):375-85. DOI:10.3322/caac.21355][Краснопольский В.И., Зароченцева Н.В., Микаелян А.В., и др. 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