GynecologyGynecologyГинекология2079-56962079-5831Consilium Medicum11475310.26442/20795696.2023.3.202296REVIEWОБЗОРReview ArticleVulvar intraepithelial neoplasia associated with HPV infection: clinical, diagnostic, therapeutic and prophylactic aspects: A reviewВульварная интраэпителиальная неоплазия, ассоциированная с ВПЧ-инфекцией: клинико-диагностические и лечебно-профилактические аспектыhttps://orcid.org/0000-0003-0574-1230MheryanAnna N.МгерянАнна Нерсесовна
Russian Federation

Cand. Sci. (Med.), Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology

кандидат медицинских наук, науч. сотр. научно-поликлинического отделения ФГБУ «НМИЦ АГП имени акад. В.И. Кулакова»

docanna@mail.ruhttps://orcid.org/0000-0001-9499-7654NazarovaNiso M.НазароваНисо Мирзоевна
Russian Federation

D. Sci. (Med.), Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology

доктор медицинских наук, вед. науч. сотр. научно-поликлинического отделения ФГБУ «НМИЦ АГП имени акад. В.И. Кулакова»

grab2@yandex.ruhttps://orcid.org/0000-0003-3993-7629PrilepskayaVera N.ПрилепскаяВера Николаевна
Russian Federation

D. Sci. (Med.), Prof., Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology

доктор медицинских наук, профессор, зав. научно-поликлиническим отделением, засл. деят. науки РФ

vprilepskaya@mail.ruKulakov National Medical Research Center for Obstetrics, Gynecology and PerinatologyФГБУ «Национальный медицинский исследовательский центр акушерства, гинекологии и перинатологии имени акад. В.И. Кулакова» Минздрава России041020232532762812703202315092023Copyright ©; 2023, Consilium MedicumCopyright ©; 2023, ООО "Консилиум Медикум"2023Consilium MedicumООО "Консилиум Медикум"https://creativecommons.org/licenses/by-nc-sa/4.0https://gynecology.orscience.ru/2079-5831/article/view/114753

The analytical review presents data from the world literature, which discusses the relevance of vulvar intraepithelial neoplasia associated with human papillomavirus (uVIN). The incidence of uVIN is steadily increasing, especially in young women, and 10–11.2% of cases can progress to vulvar carcinoma. More than 50% of uVIN cases are associated with anogenital diseases associated with the human papillomavirus, which determines the need for a comprehensive assessment and proper treatment of uVIN patients.

В аналитическом обзоре представлены данные мировой литературы, где обсуждается актуальность проблемы интраэпителиальной неоплазии вульвы, ассоциированной с вирусом папилломы человека (uVIN). Заболеваемость uVIN неуклонно растет, особенно у женщин молодого возраста, и в 10–11,2% случаев может прогрессировать до карциномы вульвы. Больше 50% случаев uVIN сочетается с заболеваниями аногенитальной области, ассоциированными с вирусом папилломы человека, что определяет необходимость комплексного обследования пациенток с uVIN и своевременного лечения.

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