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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Gynecology</journal-id><journal-title-group><journal-title xml:lang="en">Gynecology</journal-title><trans-title-group xml:lang="ru"><trans-title>Гинекология</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2079-5696</issn><issn publication-format="electronic">2079-5831</issn><publisher><publisher-name xml:lang="en">Consilium Medicum</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">27322</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Perspektivy primeneniya levonorgestrel-rilizing sistemy v premenopauze</article-title><trans-title-group xml:lang="ru"><trans-title>Перспективы применения левоноргестрел-рилизинг системы в пременопаузе</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Prilepskaya</surname><given-names>V N</given-names></name><name xml:lang="ru"><surname>Прилепская</surname><given-names>В Н</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Ostreykova</surname><given-names>L I</given-names></name><name xml:lang="ru"><surname>Острейкова</surname><given-names>Л И</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">Научный центр акушерства, гинекологии и перинатологии РАМН</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2000-04-15" publication-format="electronic"><day>15</day><month>04</month><year>2000</year></pub-date><volume>2</volume><issue>2</issue><issue-title xml:lang="en">VOL 2, NO2 (2000)</issue-title><issue-title xml:lang="ru">ТОМ 2, №2 (2000)</issue-title><fpage>54</fpage><lpage>57</lpage><history><date date-type="received" iso-8601-date="2020-04-09"><day>09</day><month>04</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2000, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2000, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2000</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://gynecology.orscience.ru/2079-5831/article/view/27322">https://gynecology.orscience.ru/2079-5831/article/view/27322</self-uri><abstract xml:lang="ru"><p>Многолетний опыт практической гинекологии показывает, что предменструальный синдром (ПМС) чаще является следствием нарушения функции высших регулирующих механизмов.Известно, что 55% женщин в пременопаузе, у которых основные гормональные параметры менструального цикла еще не изменены, страдают ПМС. Таким образом, особую значимость приобретает тактика лечения пациенток с вышеуказанной патологией. Опыт применения имплантанта, содержащего 100 мг эстрадиола и левоноргестрел-рилизинг-системы (ЛРС), у пациенток с симптомами ПМС свидетельствует о высокой эффективности предложенного метода.</p></abstract></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Комарова Ю.А. Предменструальный синдром у женщин переходного возраста. Автореф. дисс. … докт. мед. наук. М., 1987.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Barrington J.W. and Bowen-Simpkins P. (1997). The levonorgestrel intrauterine system in the management of menorrhagia. Br J Obst Gyn, 1997; 104: 614-6.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Andersson K., Mattsson L.A., Rybo G., Stadberg E. Intrauterine release of levonorgestrel - a new way of adding progestogen in hormone replacement therapy. Obst. Gyn, 1999; 79: 963-7.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Barrington J.W., O'Leary and P. Bowen-Simpkins (1997). Management of refractory pre - menstrual syndrome using subcutaneous oestradiol implants and levonorgestrel intrauterine systems. Ibid 1997; 17(4): 416-7.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Magos A.L., Brincat M. and Studd J.W.W. (1986). Treatment of premenstrual syndrome by subcutaneous oestradiol implants and cyclical oral norethisterone: placebo controlled study. Br Med J 1986; 292: 1629-33.</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Luukkainen T., Allonen H., Haukkamaa M. et al. Five years experience with levonorgestrel - releasing IUDs. Contraception 1986; 33: 139-48.</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Milsom I., Andersson K., Rybo G. A comparison of flurbiprofen, tranexamic acid and a levonorgestrel - releasing intrauterine contraceptive device in the treatment of idiopathic menorrhagia. Am J Obstet Gynecol 1991; 164: 879-83.</mixed-citation></ref></ref-list></back></article>
