GynecologyGynecologyГинекология2079-56962079-5831Consilium Medicum28571ArticlesСтатьиResearch ArticleEarly predictive markers of preeclampsiaРанние прогностические маркеры преэклампсииDubrovinaS OДубровинаС О

д-р мед. наук, проф., проф. каф. акушерства и гинекологии №1 ГБОУ ВПО РостГМУ, гл. науч. сотр. ФГБУ РНИИАП

s.dubrovina@gmail.comMutsalkhanovaYu SМуцалхановаЮ С

аспирантка ГБОУ ВПО РостГМУ

yulduzka111@mail.ruRostov State Medical University of the Ministry of Health of the Russian FederationГБОУ ВПО Ростовский государственный медицинский университет Минздрава РоссииRostov-on-Don Scientific Research Institute of Obstetrics and Pediatrics of the Ministry of Health the Russian FederationФГБУ Ростовский научно-исследовательский институт акушерства и педиатрии Минздрава РоссииRostov-on-Don Scientific Research Institute of Obstetrics and Pediatrics of the Ministry of Health the Russian FederationГБОУ ВПО Ростовский государственный медицинский университет Минздрава России15102016185VOL 18, NO5 (2016)ТОМ 18, №5 (2016)384309042020Copyright ©; 2016, Consilium MedicumCopyright ©; 2016, ООО "Консилиум Медикум"2016Consilium MedicumООО "Консилиум Медикум"https://creativecommons.org/licenses/by-nc-sa/4.0https://gynecology.orscience.ru/2079-5831/article/view/28571

Despite of preeclampsia is a leading cause of perinatal morbidity and mortality, the pathophysiology of preeclampsia remains unknown. Early prediction of preeclampsia would allow for timely initiation of preventive therapy. A combination of anamnesis, biophysical and biochemical markers are superior to other tests for early prediction of the development of preeclampsia. This article reviews the current research of the most important strategies for prediction of preeclampsia, including the use of maternal risk factors and biomarkers.

Несмотря на то что преэклампсия считается лидирующей причиной перинатальной заболеваемости и смертности, ее патофизиология остается неизвестной. Ранний прогноз преэклампсии позволит вовремя начать превентивную терапию. Сочетание анамнеза, биофизических и биохимических маркеров предпочтительнее других тестов в раннем прогнозировании развития преэклампсии. В данной статье проанализированы недавние исследования наиболее важных стратегий по прогнозу преэклампсии, включая материнские факторы риска и биомаркеры.

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