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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Gynecology</journal-id><journal-title-group><journal-title xml:lang="en">Gynecology</journal-title><trans-title-group xml:lang="ru"><trans-title>Гинекология</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2079-5696</issn><issn publication-format="electronic">2079-5831</issn><publisher><publisher-name xml:lang="en">Consilium Medicum</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">28635</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Management of endometriomas</article-title><trans-title-group xml:lang="ru"><trans-title>Менеджмент эндометриом</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Dubrovina</surname><given-names>S O</given-names></name><name xml:lang="ru"><surname>Дубровина</surname><given-names>С О</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, проф., проф. каф. акушерства и гинекологии №1 ФГБОУ ВО РостГМУ, гл. науч. сотр. Научно-исследовательского института акушерства и педиатрии</p></bio><email>s.dubrovina@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Berlim</surname><given-names>Yu D</given-names></name><name xml:lang="ru"><surname>Берлим</surname><given-names>Ю Д</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, врач гинекологического отд-ния клиники ФГБОУ ВО РостГМУ</p></bio><email>juliaberlim@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Gimbut</surname><given-names>V S</given-names></name><name xml:lang="ru"><surname>Гимбут</surname><given-names>В С</given-names></name></name-alternatives><bio xml:lang="ru"><p>канд. мед. наук, Научно-исследовательский институт акушерства и педиатрии ФГБОУ ВО РостГМУ</p></bio><email>secretary@rniiap.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Krasilnikova</surname><given-names>L V</given-names></name><name xml:lang="ru"><surname>Красильникова</surname><given-names>Л В</given-names></name></name-alternatives><bio xml:lang="ru"><p>аспирант ФГБОУ ВО РостГМУ</p></bio><email>cool.dalida2014@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Areshyan</surname><given-names>K A</given-names></name><name xml:lang="ru"><surname>Арешян</surname><given-names>К А</given-names></name></name-alternatives><bio xml:lang="ru"><p>аспирант Научно-исследовательского института акушерства и педиатрии ФГБОУ ВО РостГМУ</p></bio><email>arieshian@bk.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Rostov State Medical University</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВО «Ростовский государственный медицинский университет» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2017-08-15" publication-format="electronic"><day>15</day><month>08</month><year>2017</year></pub-date><volume>19</volume><issue>4</issue><issue-title xml:lang="en">VOL 19, NO4 (2017)</issue-title><issue-title xml:lang="ru">ТОМ 19, №4 (2017)</issue-title><fpage>30</fpage><lpage>35</lpage><history><date date-type="received" iso-8601-date="2020-04-09"><day>09</day><month>04</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2017, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2017, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://gynecology.orscience.ru/2079-5831/article/view/28635">https://gynecology.orscience.ru/2079-5831/article/view/28635</self-uri><abstract xml:lang="en"><p>Ovarian endometriomas could affect up to 44% of women with endometriosis, and are often associated with pelvic pain and infertility. Treatment options include expectant management, medical and/or surgical treatment, and in vitro fertilization. The choice of treatment depends mostly on the associated symptoms. In most cases, surgery is the preferred choice, since endometriomas do not respond to medical treatment, which may only treat associated pain. In case of infertility, in vitro fertilization and embryo transfer may be a suitable alternative to surgery, particularly when there is no associated pain. According to the best available scientific evidence, laparoscopic excision of the endometrioma wall should be considered the procedure of choice. The surgical excision may damage the ovarian reserve. At the same time, recent evidences demonstrate that part of the damage may be due to the presence of the endometrioma itself. Indication to surgical treatment should balance the possible risks of damaging the ovarian reserve with the advantages of surgery in terms of satisfactory pain relief rates and pregnancy rates, and of obtaining tissue specimen for ruling out the rare cases of unexpected ovarian malignancy. A score system to guide the clinician in the decision to perform or withhold surgery and endometriosis fertility index are presented.</p></abstract><trans-abstract xml:lang="ru"><p>Яичниковые эндометриомы могут поражать до 44% всех женщин с эндометриозом, часто ассоциированы с тазовой болью и бесплодием. Выбор лечения включает выжидательную тактику, медикаментозное или хирургическое лечение, а также экстракорпоральное оплодотворение. Предпочтение в методе лечения зависит большей частью от ассоциированных симптомов. В большинстве случаев хирургическое вмешательство является основным выбором, поскольку эндометриомы не отвечают на медикаментозное лечение, способное только облегчить боль. В случае бесплодия экстракорпоральное оплодотворение может быть подходящей альтернативной хирургическому вмешательству, особенно при отсутствии боли. Согласно научным заключениям, лапароскопическое удаление эндометриом может быть рассмотрено как процедура выбора. Однако хирургическое лечение может повредить овариальный резерв. В то же время недавние исследования подтверждают, что частично повреждения могут быть обусловлены самой эндометриомой. При выборе хирургического лечения должны быть взвешены возможные риски повреждения овариального резерва во время операции и преимущества хирургического вмешательства для облегчения болевого синдрома, а также возможность получения тканей для исключения редких случаев малигнизации. В статье представлены таблица подсчета рисков и обоснований, необходимых для клиницистов в принятии решения о необходимости выполнении хирургического лечения, и шкала подсчета индекса фертильности во время оперативного вмешательства при эндометриозе.</p></trans-abstract><kwd-group xml:lang="en"><kwd>Longidaza</kwd><kwd>endometriosis</kwd><kwd>endometrioma</kwd><kwd>therapy</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>Лонгидаза</kwd><kwd>эндометриоз</kwd><kwd>эндометриома</kwd><kwd>терапия</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Bulun S.E. Endometriosis. N Engl J Med 2009; 360 (3): 268-79. DOI: 10.1056/NEJMra0804690</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Practice Committee of the American Society for Reproductive Medicine Endometriosis and infertility: a committee opinion. Fertil Steril 2012; 98 (3): 591-8.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Practice Committee of the American Society for Reproductive Medicine. Treatment of pelvic pain associated with endometriosis: a committee opinion. Fertil Steril 2014; 101 (4): 927-35. DOI: 10.1016/j.fertnstert.2014.02.012</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Muzii L, Tucci C.D, Feliciantonio M.D et al. Management of Endometriomas. Semin Reprod Med 2017; 35 (1): 25-30. DOI: 10.1055/s-0036-1597126</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Dunselman G.A, Vermeulen N, Becker C et al. ESHRE guideline: management of women with endometriosis. Hum Reprod 2014; 29 (3): 400-12. DOI: 10.1093/humrep/det457</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Guzick D.S, Silliman N.P, Adamson G.D et al. Prediction of pregnancy in infertile women based on the American Society for Reproductive Medicine's revised classification of endometriosis. Fertil Steril 1997; 67 (5): 822-9.</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Vercellini P, Somigliana E, Viganò P et al. Surgery for endometriosis - associated infertility: a pragmatic approach. Hum Reprod 2009; 24 (2): 254-69. DOI: 10.1093/humrep/den379</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Leyland N, Casper R, Laberge P et al. Endometriosis: diagnosis and management. J Obstet Gynaecol Can 2010; 32 (7 Suppl. 2): S1-32.</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Alcá́zar J.L, Royo P, Jurado M et al. Triage for surgical management of ovarian tumors in asymptomatic women: assessment of an ultrasoundbased scoring system. Ultrasound Obstet Gynecol 2008; 32 (2): 220-5.</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Valentin L, Ameye L, Franchi D et al. Risk of malignancy in unilocular cysts: a study of 1148 adnexal masses classified as unilocular cysts at transvaginal ultrasound and review of the literature. Ultrasound Obstet Gynecol 2013; 41 (1): 80-9. DOI: 10.1002/uog.12308</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>Gonçalves F.C, Andres M.P, Passman L.J et al. A systematic review of ultrasonography - guided transvaginal aspiration of recurrent ovarian endometrioma. Int J Gynaecol Obstet 2016; 134 (1): 3-7. DOI: 10.1016/j.ijgo.2015.10.021</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>Padilla S.L. Ovarian abscess following puncture of an endometrioma during ultrasound - guided oocyte retrieval. Hum Reprod 1993; 8 (8): 1282-3.</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>Muzii L, Marana R, Caruana P et al. Laparoscopic findings after transvaginal ultrasoundguided aspiration of ovarian endometriomas. Hum Reprod 1995; 10 (11): 2902-3.</mixed-citation></ref><ref id="B14"><label>14.</label><mixed-citation>Chapron C, Vercellini P, Barakat H et al. Management of ovarian endometriomas. Hum Reprod Update 2002; 8 (6): 591-7.</mixed-citation></ref><ref id="B15"><label>15.</label><mixed-citation>Alborzi S, Momtahan M, Parsanezhad M.E et al. A prospective, randomized study comparing laparoscopic ovarian cystectomy versus fenestration and coagulation in patients with endometriomas. Fertil Steril 2004; 82 (6): 1633-7.</mixed-citation></ref><ref id="B16"><label>16.</label><mixed-citation>Carmona F, Martínez Zamora M.A et al. Ovarian cystectomy versus laser vaporization in the treatment of ovarian endometriomas: a randomized clinical trial with a fiveyear followup. Fertil Steril 2011; 96 (1): 251-4.</mixed-citation></ref><ref id="B17"><label>17.</label><mixed-citation>Hart R.J, Hickey M, Maouris P et al. Excisional surgery versus ablative surgery for ovarian endometriomata. Cochrane Database Syst Rev 2008; 2: CD004992. DOI: 10.1002/14651858.CD004992.pub3</mixed-citation></ref><ref id="B18"><label>18.</label><mixed-citation>Tsolakidis D, Pados G, Vavilis D et al. The impact on ovarian reserve after laparoscopic ovarian cystectomy versus three - stage management in patients with endometriomas: a prospective randomized study. Fertil Steril 2010; 94 (1): 71-7. DOI: 10.1016/j.fertnstert.2009.01.138</mixed-citation></ref><ref id="B19"><label>19.</label><mixed-citation>Kondo W, Bourdel N, Zomer M.T et al. Laparoscopic cystectomy for ovarian endometrioma - a simple stripping technique should not be used. J Endometr 2011; 3 (3): 125-34.</mixed-citation></ref><ref id="B20"><label>20.</label><mixed-citation>Дубровина С.О., Берлим Ю.Д., Гимбут В.С. и др. Современные представления об эндометриоидных кистах яичников. Проблемы репродукции. 2015; 21 (3): 98-105.</mixed-citation></ref><ref id="B21"><label>21.</label><mixed-citation>Bourdel N, Roman H, Mage G, Canis M. Surgery for the management of ovarian endometriomas: from the physiopathology to the pre -, peri - and postoperative treatment. Gynecol Obstet Fertil 2011; 39 (12): 709-21. DOI: 10.1016/j.gyobfe.2011.07.051</mixed-citation></ref><ref id="B22"><label>22.</label><mixed-citation>Coric M, Barisic D, Pavicic D et al. Electrocoagulation versus suture after laparoscopic stripping of ovarian endometriomas assessed by antral follicle count: preliminary results of randomized clinical trial. Arch Gynecol Obstet 2011; 283 (2): 373-8. DOI: 10.1007/s00404-010-1676-x</mixed-citation></ref><ref id="B23"><label>23.</label><mixed-citation>Guo S.W. Recurrence of endometriosis and its control. Hum Reprod Update 2009; 15 (4): 441-61. DOI: 10.1093/humupd/dmp007</mixed-citation></ref><ref id="B24"><label>24.</label><mixed-citation>Busacca M, Marana R, Caruana P et al. Recurrence of ovarian endometrioma after laparoscopic excision. Am J Obstet Gynecol 1999; 180 (3 Pt. 1): 519-23.</mixed-citation></ref><ref id="B25"><label>25.</label><mixed-citation>Morgante G, Ditto A, La Marca A et al. Low - dose danazol after combined surgical and medical therapy reduces the incidence of pelvic pain in women with moderate and severe endometriosis. Hum Reprod 1999; 14 (9): 2371-4.</mixed-citation></ref><ref id="B26"><label>26.</label><mixed-citation>Yap C, Furness S, Farquhar C et al. Pre and post operative medical therapy for endometriosis surgery. Cochrane Database Syst Rev 2004; 3: CD003678.</mixed-citation></ref><ref id="B27"><label>27.</label><mixed-citation>Seracchioli R, Mabrouk M, Manuzzi L et al. Post - operative use of oral contraceptive pills for prevention of anatomical relapse or symptom - recurrence after conservative surgery for endometriosis. Hum Reprod 2009; 24 (11): 2729-35. DOI: 10.1093/humrep/dep259</mixed-citation></ref><ref id="B28"><label>28.</label><mixed-citation>Vercellini P, D E Matteis S, Somigliana E et al. Long - term adjuvant therapy for the prevention of postoperative endometrioma recurrence: a systematic review and meta - analysis. Acta Obstet Gynecol Scand 2013; 92 (1): 8-16. DOI: 10.1111/j.1600-0412.2012.01470.x</mixed-citation></ref><ref id="B29"><label>29.</label><mixed-citation>Seracchioli R, Mabrouk M, Frascà C et al. Long - term cyclic and continuous oral contraceptive therapy and endometrioma recurrence: a randomized controlled trial. Fertil Steril 2010; 93 (1): 52-6. DOI: 10.1016/j.fertnstert.2008.09.052</mixed-citation></ref><ref id="B30"><label>30.</label><mixed-citation>Seracchioli R, Mabrouk M, Frascà C et al. Long - term oral contraceptive pills and postoperative pain management after laparoscopic excision of ovarian endometrioma: a randomized controlled trial. Fertil Steril 2010; 94 (2): 464-71. DOI: 10.1016/j.fertnstert.2009.03.083</mixed-citation></ref><ref id="B31"><label>31.</label><mixed-citation>Muzii L, Maneschi F, Marana R et al. Oral estroprogestins after laparoscopic surgery to excise endometriomas: continuous or cyclic administration? Results of a multicenter randomized study. J Minim Invasive Gynecol 2011; 18 (2): 173-8. DOI: 10.1016/j.jmig.2010.11.004</mixed-citation></ref><ref id="B32"><label>32.</label><mixed-citation>Muzii L, Di Tucci C, Achilli C et al. Continuous versus cyclic oral contraceptives after laparoscopic excision of ovarian endometriomas: a systematic review and metaanalysis. Am J Obstet Gynecol 2016; 214 (2): 203-11. DOI: 10.1016/j.ajog.2015.08.074</mixed-citation></ref><ref id="B33"><label>33.</label><mixed-citation>Vercellini P, Chapron C, De Giorgi O et al. Coagulation or excision of ovarian endometriomas? Am J Obstet Gynecol 2003; 188 (3): 606-10.</mixed-citation></ref><ref id="B34"><label>34.</label><mixed-citation>Llarena N, Flyckt R. Strategies to preserve and optimize fertility for patients with endometriosis. J Endometr Pelvic Pain Disord 2017; 9 (2): 98-104.</mixed-citation></ref><ref id="B35"><label>35.</label><mixed-citation>Busacca M, Riparini J, Somigliana E et al. Postsurgical ovarian failure after laparoscopic excision of bilateral endometriomas. Am J Obstet Gynecol 2006; 195 (2): 421-5.</mixed-citation></ref><ref id="B36"><label>36.</label><mixed-citation>Coccia M.E, Rizzello F, Mariani G et al. Ovarian surgery for bilateral endometriomas influences age at menopause. Hum Reprod 2011; 26 (11): 3000-7. DOI: 10.1093/humrep/der286</mixed-citation></ref><ref id="B37"><label>37.</label><mixed-citation>Goodman L.R, Goldberg J.M, Flyckt R.L et al. Effect of surgery on ovarian reserve in women with endometriomas, endometriosis and controls. Am J Obstet Gynecol 2016; 215 (5): 589.e1-589.e6. DOI: 10.1016/j.ajog.2016.05.029</mixed-citation></ref><ref id="B38"><label>38.</label><mixed-citation>Chen Y, Pei H, Chang Y et al. The impact of endometrioma and laparoscopic cystectomy on ovarian reserve and the exploration of related factors assessed by serum anti - Mullerian hormone: a prospective cohort study. J Ovarian Res 2014; 7: 108. DOI: 10.1186/s13048-014-0108-0</mixed-citation></ref><ref id="B39"><label>39.</label><mixed-citation>Benaglia L, Bermejo A, Somigliana E et al. In vitro fertilization outcome in women with unoperated bilateral endometriomas. Fertil Steril 2013; 99 (6): 1714-9. DOI: 10.1016/j.fertnstert.2013.01.110</mixed-citation></ref><ref id="B40"><label>40.</label><mixed-citation>Sanchez A.M, Viganò P, Somigliana E. The distinguishing cellular and molecular features of the endometriotic ovarian cyst: from pathophysiology to the potential endometrioma - mediated damage to the ovary. Hum Reprod Update 2014; 20 (2): 217-30. DOI: 10.1093/humupd/dmt053</mixed-citation></ref><ref id="B41"><label>41.</label><mixed-citation>Ding Y, Yuan Y, Ding J et al. Comprehensive Assessment of the Impact of Laparoscopic Ovarian Cystectomy on Ovarian Reserve. J Minim Invasive Gynecol 2015; 22 (7): 1252-9. DOI: 10.1016/j.jmig.2015.07.011</mixed-citation></ref><ref id="B42"><label>42.</label><mixed-citation>Celik H.G, Dogan E, Okyay E et al. Effect of laparoscopic excision of endometriomas on ovarian reserve: serial changes in the serum antimüllerian hormone levels. Fertil Steril 2012; 97 (6): 1472-8. DOI: 10.1016/j.fertnstert.2012.03.027</mixed-citation></ref><ref id="B43"><label>43.</label><mixed-citation>Ercan C.M, Sakinci M, Duru N.K et al. Antimullerian hormone levels after laparoscopic endometrioma stripping surgery. Gynecol Endocrinol 2010; 26 (6): 468-72. DOI: 10.3109/09513591003632134</mixed-citation></ref><ref id="B44"><label>44.</label><mixed-citation>Hirokawa W, Iwase A, Goto M et al. The post - operative decline in serum anti - Mullerian hormone correlates with the bilaterality and severity of endometriosis. Hum Reprod 2011; 26 (4): 904-10. DOI: 10.1093/humrep/der006</mixed-citation></ref><ref id="B45"><label>45.</label><mixed-citation>Hamdan M, Dunselman G, Li TC et al. The impact of endometrioma on IVF/ICSI outcomes: a systematic review and meta - analysis. Hum Reprod Update 2015; 21 (6): 809-25. DOI: 10.1093/humupd/dmv035</mixed-citation></ref><ref id="B46"><label>46.</label><mixed-citation>Tsoumpou I, Kyrgiou M, Gelbaya T.A et al. The effect of surgical treatment for endometrioma on in vitro fertilization outcomes: a systematic review and meta - analysis. Fertil Steril. 2009; 92 (1): 75-87. DOI: 10.1016/j.fertnstert.2008.05.049</mixed-citation></ref><ref id="B47"><label>47.</label><mixed-citation>Benschop L, Farquhar C, van der Poel N et al. Interventions for women with endometrioma prior to assisted reproductive technology. Cochrane Database Syst Rev 2010; 11: CD008571. DOI: 10.1002/14651858.CD008571.pub2</mixed-citation></ref><ref id="B48"><label>48.</label><mixed-citation>Almog B, Sheizaf B, Shalom-Paz E et al. Effects of excision of ovarian endometrioma on the antral follicle count and collected oocytes for in vitro fertilization. Fertil Steril 2010; 94 (6): 2340-2. DOI: 10.1016/j.fertnstert.2010.01.055</mixed-citation></ref><ref id="B49"><label>49.</label><mixed-citation>Somigliana E, Ragni G, Benede F et al. Does laparoscopic excision of endometriotic ovarian cysts significantly affect ovarian reserve? Insights from IVF cycles. Hum Reprod 2003; 18 (11): 2450-3.</mixed-citation></ref><ref id="B50"><label>50.</label><mixed-citation>Esinler I, Bozdag G, Aybar F et al. Outcome of in vitro fertilization/intracytoplasmic sperm injection after laparoscopic cystectomy for endometriomas. Fertil Steril 2006; 85 (6): 1730-5.</mixed-citation></ref><ref id="B51"><label>51.</label><mixed-citation>Ho H.Y, Lee R.K, Hwu Y.M et al. Poor response of ovaries with endometrioma previously treated with cystectomy to controlled ovarian hyperstimulation. J Assist Reprod Genet 2002; 19 (11): 507-11.</mixed-citation></ref><ref id="B52"><label>52.</label><mixed-citation>Garcia-Velasco J.A, Somigliana E. Management of endometriomas in women requiring IVF: to touch or not to touch. Hum Reprod 2009; 24 (3): 496-501. DOI: 10.1093/humrep/den398</mixed-citation></ref><ref id="B53"><label>53.</label><mixed-citation>Adamson G.D, Pasta D.J. Endometriosis fertility index: the new, validated endometriosis staging system. Fertil Steril 2010; 94 (5): 1609-15. DOI: 10.1016/j.fertnstert.2009.09.035</mixed-citation></ref><ref id="B54"><label>54.</label><mixed-citation>Luciano D.E, Roy G, Luciano A.A. Adhesion reformation after laparoscopic adhesiolysis: where, what type, and in whom they are most likely to recur. J Minim Invasive Gynecol 2008; 15 (1): 44-8. DOI: 10.1016/j.jmig.2007.09.012</mixed-citation></ref><ref id="B55"><label>55.</label><mixed-citation>Fayez J.A, Vogel M.F. Comparison of different treatment methods of endometriomas by laparoscopy. Obstet Gynecol 1991; 78 (4): 660-5.</mixed-citation></ref><ref id="B56"><label>56.</label><mixed-citation>Ahmad G, O'Flynn H, Hindocha A et al. Barrier agents for adhesion prevention after gynaecological surgery. Cochrane Database Syst Rev 2015; 4: CD000475. DOI: 10.1002/14651858.CD000475.pub3</mixed-citation></ref><ref id="B57"><label>57.</label><mixed-citation>Tulandi T, Closon F, Czuzoj-Shulman N et al. Adhesion Barrier Use After Myomectomy and Hysterectomy: Rates and Immediate Postoperative Complications. Obstet Gynecol 2016; 127 (1): 23-8. DOI: 10.1097/AOG.0000000000001186</mixed-citation></ref><ref id="B58"><label>58.</label><mixed-citation>Петрович Е.А., Манухин И.Б. Инновационный подход к лечению трубно - перитонеального бесплодия. Вопр. гинекологии, акушерства и перинатологии. 2010; 9 (6): 5-10.</mixed-citation></ref><ref id="B59"><label>59.</label><mixed-citation>Смирнова Л.Е., Умаханова М.М., Торчинов А.М. Современные взгляды на спаечный процесс в брюшной полости при трубно - перитонеальном бесплодии. Акушерство и гинекология. 2016; 11. 148-52.</mixed-citation></ref><ref id="B60"><label>60.</label><mixed-citation>Стрижаков А.Н., Пирогова М.Н., Шахламова М.Н. и др. Профилактика и лечение спаечного процесса после оперативного лечения апоплексии яичника. Рос. вестн. акушера - гинеколога. 2015; 2: 36-42.</mixed-citation></ref><ref id="B61"><label>61.</label><mixed-citation>Манухин И.Б., Колесов А.А., Бекмурзаева Л.К., Петрович Е.А. Профилактика спаечного процесса после оперативных вмешательств на яичниках и маточных трубах. Вопр. гинекологии, акушерства и перинатологии. 2007; 6 (1).</mixed-citation></ref></ref-list></back></article>
