GynecologyGynecology2079-56962079-5831Consilium Medicum3007710.26442/2079-5696_20.1.96-101Research ArticleMethod of photothermal tissue reconstruction in modern medical practice using ER:YAG laserKulikovI Aginkulikov@yandex.ruSpokoynyyL B-GorbunovaE A-ApolikhinaI A-V.I.Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology of the Ministry of Health of the Russian FederationI.M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian FederationEuropean Laser Academy of Health (LA&HA)150220182019610109042020Copyright © 2018, Consilium Medicum2018This article is devoted to the review of domestic and foreign data on the efficacy and safety of non-invasive erbium laser therapy aimed at increasing the tone of the pelvic floor muscles. The search for literature data allowed to reveal a lot of studies describing the successful experience of non-invasive laser procedures in gynecology, as well as not only the high effectiveness of the method, but also its safety. This type of therapy represents a promising treatment technology with a high level of efficacy and an optimal safety profile.urinary incontinencepelvic floor prolapsevaginal relaxation syndromeнедержание мочипролапс мышц тазового днасиндром вагинальной релаксации[Vizintin Z.et al. Novel minimally invasive VSP Er:YAG laser treatments in Gynecology. J Laser Health Academy 2012; 1.][Fistonic I et al. Minimally invasive laser procedure for early stages of stress urinary incontinence (SUI). J Laser Health Academy 2012; 1.][Gaviria J et al. Laser Vaginal Tightening (LVT) - evaluation of a novel noninvasive laser treatment for vaginal relaxation syndrome, J Laser Health Academy 2012; 1.][Sencar S, Bizjak-Ogrinc U. Improvement of stress urinary incontinence in women after Er:YAG laser treatment, ICS Barcelona. 2013.][Garcia V et al. Laser Vaginal Tightening and Sexual Gratification, Laser Europe, London. 2012.][Bizjak-Ogrinc U, Sencar S. Non-surgical minimally invasive Er:YAG laser treatment for higher-grade cystocele, 38th IUGA conference. Dublin, 2013.][Gaspar A. Comparison of new minimally invasive Er:YAG laser 26. treatment and hormonal replacement therapy in the treatment of vaginal atrophy. Climacteric 2014; 17 (Suppl. 1): 124.][Bezmenko A.A et al. Treatment of stress urinary incontinence with Er:YAG laser: some biochemical parameters of connective tissue metabolism. J Experiment Clin Urology 2014.][Bezmenko A.A et al. Conservative ways of urinary stress incontinence treatment. J Rus Military Med Academy 2014.][Bezmenko A.A et al. Morphological Substantiation of Applying the Er:YAG laser for the treatment of Stress Urinary Incontinence in Women. J Obstet Women Dis 2014; 3.][Lukanovic A. et al. Non-ablative Er:YAG laser therapy effect on SUI related quality of life and sexual function: a randomized controlled trial, ICS conference. Rio de Janeiro, 2014.][Bojanini B.J.F, Mejía C.A.M. Laser Treatment of Vaginal Atrophy in Post-menopause and Post-gynecological Cancer Patients. J Laser Health Academy 2014; 1: 65-71.][Gambacciani M. et al. Short term effect of vaginal erbium laser on the genitourinary syndrome of menopause. Minerva Ginecol 2015.][Gambacciani M, Levancini M. Vaginal Erbium Laser: the Second Generation Thermotherapy for the Genitourinary Syndrome of Menopause (GSM) in Breast Cancer Survivors. A preliminary report of a pilot study. Ital J Gynecol Obstet 2015; 27 (1).][Gambacciani M, Levancini M, Cervini M. Vaginal erbium laser: the second-generation thermotherapy for the genitourinary syndrome of menopause. Climacteric 2015; 18: 1-7.][Gambacciani M, Torelli M.G, Martella L. et al. Rationale and design for the Vaginal Erbium Laser Academy Study (VELAS): an international multicenter observational study on genitourinary syndrome of menopause and stress urinary incontinence. Climacteric 2015; 18 (Suppl. 1): 43-8.][Vizintin Z, Lukac M, Kazic M, Tettamanti M. Erbium laser in Gynecology. Climacteric 2015: 18 (Suppl.): 4-8.][Gaspar A, Brandi H, Gomez V, Luque D. Efficacy of Erbium:YAG Laser Treatment Compared to Topical Estriol Treatment for Symptoms of Genitourinary Syndrome of Menopause. Laser Surg Medicine 2016.][Tien Y.W, Hsiao S.M, Lee C.N, Lin H.H. Effects of laser procedure for female urodynamic stress incontinence on pad weight, urodynamics, and sexual function. Int Urogynecol J 2016. DOI: 10.1007/s00192-016-3129-y][Gambacciani M, Levancini M. Vaginal erbium laser as second-generation thermotherapy for the genitourinary syndrome of menopause: a pilot study in breast cancer survivors, Menopause. J North Am Menopause Soc 2016; 24. DOI: 10.1097/GME.0000000000000761][Fistonic N, Fistonic I, Lukanovic A. Franic. First assessment of short term efficacy of Er:YAG laser treatment on stress urinary incontinence in women: prospective cohort study. Climacteric 2015; 18 (Suppl.): 37-42.][Fistonic N, Fistonic I, Findri Gustek ŠS et al. Minimally invasive, non-ablative Er:YAG laser treatment of stress urinary incontinence in women - a pilot study. J Laser Med Sci 2016.][Pardo J, Sola V, Morales A. Treatment of female stress urinary incontinence with Erbium YAG laser in non-ablative mode. Eur J Obstet Gynecol Reprod Biol 2016; 204: 1-4.][Аполихина И.А., Горбунова Е.А., Одинокова В.А Малоинвазивные инновационные лазерные технологии в гинекологической практике. Акуш. и гинекол. 2014; 11: 17-22.][Khalafalla M.M, Elbiaa A.M, Abdelazim I.A, Hussain M. Minimal Invasive Laser Treatment for Female Stress Urinary Incontinence. Obstet Gynecol Int J 2015; 2 (2): 00035.][Ogrinc U.B, Sencar S, Lenasi H. Novel Minimally Invasive Laser Treatment of Urinary Incontinence in Women. Laser Surg Medicine 2015.]