GynecologyGynecologyГинекология2079-56962079-5831Consilium Medicum3349210.26442/20795696.2019.2.190387ArticlesСтатьиReview ArticleEffects of combined oral contraceptives on the sexuality and quality of life of womenЭффекты комбинированной оральной контрацепции на сексуальность и качество жизни женщинGabidullinaRushanya IГабидуллинаРушанья Исмагиловна

D. Sci. (Med.)

д-р мед. наук, проф. каф. акушерства и гинекологии им. В.С. Груздева

ru.gabidullina@yandex.ruGalimyanovaElvira IГалимьяноваЭльвира Ильгизаровна

аспирант каф. акушерства и гинекологии им. В.С. Груздева

dr.ellie17@gmail.comBagirliRufat RБагирлиРуфат оглы

Graduate Student

аспирант каф. акушерства и гинекологии им. В.С. Груздева

SharapovaAnastasiya MШараповаАнастасия Михайловна

Gynecologist

акушер-гинеколог

Kazan State Medical UniversityФГБОУ ВО КГМУPovolzhskiy Center of oncodiagnosticsПоволжский центр онкодиагностики15042019212VOL 21, NO2 (2019)ТОМ 21, №2 (2019)667016042020Copyright ©; 2019, Consilium MedicumCopyright ©; 2019, ООО "Консилиум Медикум"2019Consilium MedicumООО "Консилиум Медикум"https://creativecommons.org/licenses/by-nc-sa/4.0https://gynecology.orscience.ru/2079-5831/article/view/33492

Aim. Examine the impact of combined oral contraceptive on sexuality and the quality of women’s life. Materials and methods. The article presents a review of Electronic literature databases MEDLINE, PubMed, EMBASE, Cochrane Library and Elibrary. Results. Since its first introduction in the 1960s, hormonal contraception has been widely used as a highly effective birth control method. However, the hormonal components of oral contraceptives affect the neuroendocrine system of women, exerting various effects on mood, libido, on sexuality and quality of life in general. Based on literature data the effect of contraception on sexuality, the physiological and emotional state of women are various. It is known that the hormonal supplementation of sexual desire is associated with ovarian hormones. At the same time, a high concentration of estrogen and testosterone receptors has been determined in the hypothalamus, which controls sexual function and mood. The mechanisms to implement the effects of androgen and progesterone on sexual desire are ambiguous. It was found a positive relationship between a sexual interest, sexual response, sexual fantasy, frequency of sexual intercourse and a testosterone level. At the same time, it is known that estradiol can increase the ability of women to orgasmic response and sexual satisfaction by acting on specific brain structures. Conclusion. The effect of contraception on women’s sexual life is an important factor when choosing a method of contraception and an integral part in the obstetrician-gynecologist’s practice, which requires further research in this direction.

Цель. Изучить влияние комбинированных оральных контрацептивов на сексуальность и качество жизни женщин. Материал и методы. В статье представлен обзор литературы по результатам поиска исследований в электронных ресурсах MEDLINE, PubMed, EMBASE, Cochrane Library и Elibrary. Результаты. С начала своего первого применения в 1960 г. гормональная контрацепция получила всемирное признание как высокоэффективный метод контроля над рождаемостью. Однако гормональные компоненты оральных контрацептивов влияют на нейроэндокринную систему женщин, оказывая различные эффекты на настроение, либидо и в целом на сексуальность и качество жизни. Литературные данные о влиянии контрацепции на сексуальность, физиологическое и эмоциональное состояние женщин неоднозначны. Известно, что гормональное обеспечение полового влечения связано с гормонами яичников. В то же время в гипоталамусе, контролирующем половую функцию и настроение, определяется высокая концентрация рецепторов к эстрогенам и тестостерону. Механизмы реализации эффектов андрогенов и прогестерона на половое влечение неоднозначны. Выявлена положительная связь между сексуальным интересом, сексуальным реагированием, сексуальным фантазированием, частотой половых актов и уровнем тестостерона в плазме крови. При этом известно, что эстрадиол, воздействуя на специфические структуры головного мозга, может повышать способность женщин к оргастическому реагированию и половому удовлетворению. Заключение. Влияние контрацепции на сексуальную жизнь женщин, несомненно, является важным фактором при принятии решения о выборе способа контрацепции и неотъемлемой составляющей в практике акушера-гинеколога, что требует дальнейших исследований в данном направлении.

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