GynecologyGynecology2079-56962079-5831Consilium Medicum3410810.26442/20795696.2020.5.200416Research ArticleFeatures of the ovarian reserve of women of reproductive age suffering from autoimmune diseasesAndreevaElena N.<p>D. Sci. (Med.), Endocrinology Research Centre, Yevdokimov Moscow State University of Medicine and Dentistry</p>endogin@mail.ruhttps://orcid.org/0000-0001-8425-0020GrigoryanOlga R.<p>D. Sci. (Med.), Endocrinology Research Centre</p>iceberg1995@mail.ruhttps://orcid.org/0000-0003-4979-7420AbsatarovaYulia S.<p>Cand. Sci (Med.), Endocrinology Research Centre</p>korsil2008@yandex.ruhttps://orcid.org/0000-0003-0696-5367YarovayaIrina S.<p>Cand. Sci (Med.), Endocrinology Research Centre</p>yarovaya.is@yandex.ruhttps://orcid.org/0000-0003-3222-5936MikheevRobert K.<p>Student, Endocrinology Research Centre, Yevdokimov Moscow State University of Medicine and Dentistry</p>mikheev-robert@list.ruhttps://orcid.org/0000-0001-5826-3186Endocrinology Research CentreYevdokimov Moscow State University of Medicine and DentistryEndocrinology Research Centre, Moscow23112020225273024052020Copyright © 2020, Consilium Medicum2020<p>The reproductive potential of a woman depends on indicators of the ovarian reserve, such as the anti-Muller hormone (AMH) and the number of antral follicles (NAF). Autoimmune diseases have a significant effect on fertility and contribute to the development of premature ovarian failure.</p>
<p><strong>Aim.</strong>To evaluate the parameters of the ovarian reserve in patients with type 1 diabetes mellitus, carriers of antibodies to the thyroid gland in a state of euthyroidism and compare them with similar parameters in healthy women.</p>
<p><strong>Materials and methods.</strong>In the first block of the study, the level of AMH, follicle-stimulating hormone, luteinizing hormone, NAF was studied among 224 women with diabetes and 230 healthy women in the control group. In block II, the level of the above hormonal indices was studied in 35 carriers of antithyroid antibodies in the state of euthyroidism and 35 healthy women.</p>
<p><strong>Results.</strong>In patients with type 1 diabetes, the level of AMH, NAF was statistically significantly lower when compared with the control group. Among carriers of antithyroid antibodies and healthy women, no difference in AMH and NAF was found.</p>
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