GynecologyGynecology2079-56962079-5831Consilium Medicum4484810.26442/20795696.2020.6.200460Research ArticlePapillomaviral infection and cervical diseases in pregnant women. Risk factors of social status, reproductive and contraceptive behaviorBebnevaTamara N.<p>Cand. Sci (Med.)</p>bebn@mail.ruhttps://orcid.org/0000-0003-1095-2008DikkeGalina B.<p>D. Sci. (Med.)</p>galadikke@yandex.ruhttps://orcid.org/0000-0001-9524-8962People’s Friendship University of RussiaInozemtsev Academy of Medical Education24122020226747923092020Copyright © 2020, Consilium Medicum2020<p><strong>Aim. </strong>To determine the risk factors for human papillomavirus of high carcinogenic risk (HPV HCR) and cervical diseases (CD) in pregnant women associated with the social status, reproductive and contraceptive behavior.</p>
<p><strong>Materials and methods. </strong>Design: open-label comparative non-interventional cohort study in parallel groups. The total number of patients 330 people, of whom 148 women were negative for HPV and 182 women were positive. They were divided into 4 groups depending on the presence or absence of CD. Methods: analysis of anamnesis data, general clinical, test Kvant-21 to determine HPV, cytological examination, extended colposcopy.</p>
<p><strong>Results. </strong>The most significant risk factors for HPV HRS infection were identified: history of mycoplasma infection (OR 5.9) and BV (OR 5.3), alcohol consumption (OR 4.0). A history of STIs (trichomoniasis and chlamydial infection), as well as more than 3 sexual partners (OR 2.7) were also significant. The most significant risk factors for CD in HPV-infected women were: age over 35 years (OR 3.8), a history of bacterial vaginosis (OR 3.0), and lack of regular screening (OR 2.4). The coitarche earlier than 16 years old (OR 2.2) also mattered. There were also found factors indicating a low risk of HPV infection the use of condoms (OR 0.3), and a low risk of CD was indicated by age under 25 years (OR 0.2) and regular screening (OR 0.3).</p>
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