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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Gynecology</journal-id><journal-title-group><journal-title xml:lang="en">Gynecology</journal-title><trans-title-group xml:lang="ru"><trans-title>Гинекология</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2079-5696</issn><issn publication-format="electronic">2079-5831</issn><publisher><publisher-name xml:lang="en">Consilium Medicum</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">627153</article-id><article-id pub-id-type="doi">10.26442/20795696.2024.2.202716</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>REVIEW</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОБЗОР</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Isthmocele: controversial issues of terminology, diagnosis and treatment. A review</article-title><trans-title-group xml:lang="ru"><trans-title>Истмоцеле: дискуссионные вопросы терминологии, диагностики и лечения</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9183-7030</contrib-id><name-alternatives><name xml:lang="en"><surname>Podzolkova</surname><given-names>Natalia M.</given-names></name><name xml:lang="ru"><surname>Подзолкова</surname><given-names>Наталия Михайловна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>D. Sci. (Med.), Prof., Russian Medical Academy of Continuous Professional Education, Botkin City Clinical Hospital</p></bio><bio xml:lang="ru"><p>д-р мед. наук, проф., зав. каф. акушерства и гинекологии ФГБОУ ДПО РМАНПО, вед. науч. сотр. ГБУЗ «ГКБ им. С.П. Боткина»</p></bio><email>podzolkova@gmail.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Demidov</surname><given-names>Anton V.</given-names></name><name xml:lang="ru"><surname>Демидов</surname><given-names>Антон Владимирович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Chief doctor, Pletnev City Clinical Hospital</p></bio><bio xml:lang="ru"><p>глав. врач ГБУЗ «ГКБ им. Д.Д. Плетнева»</p></bio><email>yuliya.sheveleva.97@mail.ru</email><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5351-0854</contrib-id><name-alternatives><name xml:lang="en"><surname>Osadchev</surname><given-names>Vasilii B.</given-names></name><name xml:lang="ru"><surname>Осадчев</surname><given-names>Василий Борисович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Cand. Sci. (Med.), Assoc. Prof., Russian Medical Academy of Continuous Professional Education, Pletnev City Clinical Hospital</p></bio><bio xml:lang="ru"><p>канд. мед. наук, доц., доц. каф. акушерства и гинекологии ФГБОУ ДПО РМАНПО, зав. гинекологическим отд-нием ГБУЗ «ГКБ им. Д.Д. Плетнева»</p></bio><email>yuliya.sheveleva.97@mail.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6260-2734</contrib-id><name-alternatives><name xml:lang="en"><surname>Babkov</surname><given-names>Kirill V.</given-names></name><name xml:lang="ru"><surname>Бабков</surname><given-names>Кирилл Владимирович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Cand. Sci. (Med.), Assoc. Prof., Russian Medical Academy of Continuous Professional Education, Pletnev City Clinical Hospital</p></bio><bio xml:lang="ru"><p>канд. мед. наук, доц., доц. каф. акушерства и гинекологии ФГБОУ ДПО РМАНПО, врач – акушер-гинеколог гинекологического отд-ния ГБУЗ «ГКБ им. Д.Д. Плетнева»</p></bio><email>kirill.babkov@mail.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1753-0537</contrib-id><name-alternatives><name xml:lang="en"><surname>Denisova</surname><given-names>Yulia V.</given-names></name><name xml:lang="ru"><surname>Денисова</surname><given-names>Юлия Вадимовна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Assistant, Russian Medical Academy of Continuous Professional Education, Pletnev City Clinical Hospital</p></bio><bio xml:lang="ru"><p>ассистент каф. акушерства и гинекологии ФГБОУ ДПО РМАНПО, врач – акушер-гинеколог гинекологического отд-ния ГБУЗ «ГКБ им. Д.Д. Плетнева»</p></bio><email>yuliya.sheveleva.97@mail.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff3"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Russian Medical Academy of Continuous Professional Education</institution></aff><aff><institution xml:lang="ru">ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">2Botkin City Clinical Hospital</institution></aff><aff><institution xml:lang="ru">ГБУЗ «Городская клиническая больница им С.П. Боткина» Департамента здравоохранения г. Москвы</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">Pletnev City Clinical Hospital</institution></aff><aff><institution xml:lang="ru">ГБУЗ «Городская клиническая больница им. Д.Д. Плетнева» Департамента здравоохранения г. Москвы</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2024-06-10" publication-format="electronic"><day>10</day><month>06</month><year>2024</year></pub-date><volume>26</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>119</fpage><lpage>127</lpage><history><date date-type="received" iso-8601-date="2024-02-18"><day>18</day><month>02</month><year>2024</year></date><date date-type="accepted" iso-8601-date="2024-06-06"><day>06</day><month>06</month><year>2024</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2024, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2024, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://gynecology.orscience.ru/2079-5831/article/view/627153">https://gynecology.orscience.ru/2079-5831/article/view/627153</self-uri><abstract xml:lang="en"><p>The frequency of abdominal delivery in the world is steadily rising. Since the latter is associated with a lot of complications compared with vaginal delivery, the increase in the proportion of deliveries in women with a uterine scar through the natural birth canal is an important strategic goal of the obstetrics and gynecology community. In addition, it is established that every second patient after a cesarean section develops a defect in the scar area, which is often accompanied by various disorders of the menstrual cycle (in 25,5% of cases – abnormal uterine bleeding) and can cause secondary infertility. Both assessment of the risk of scar failure at the stage of preconceptional preparation and timely detection and treatment of isthmocele symptoms are still serious challenges facing obstetricians and gynecologists. Clinical guidelines devoted to the cesarean scar defect problem have not yet been developed. This review presents the quintessence of modern data on possible risk factors, clinical manifestations with a detailed consideration of pathophysiological mechanisms, diagnostic tools and correction methods of symptomatic isthmocele and uterine scar defect with a detailed description of indications and a comparative assessment of their effectiveness in order to standardize approaches to the diagnosis and treatment of these pathological conditions.</p></abstract><trans-abstract xml:lang="ru"><p>Частота абдоминального родоразрешения в мире неуклонно растет. Поскольку последнее сопряжено с большим, в сравнении с вагинальными родами, количеством осложнений, увеличение доли родов у женщин с рубцом на матке через естественные родовые пути служит важной стратегической задачей акушерско-гинекологического сообщества. Помимо этого установлено, что у каждой второй пациентки после кесарева сечения формируется дефект области рубца, который часто сопровождается различными нарушениями менструального цикла (в 25,5% случаев – аномальными маточными кровотечениями) и может служить причиной вторичного бесплодия. Как оценка риска развития несостоятельности рубца на этапе прегравидарной подготовки, так и своевременное выявление и лечение симптомов истмоцеле являются серьезными задачами специалистов акушерско-гинекологического профиля. Клинические рекомендации, посвященные проблеме дефекта рубца на матке после кесарева сечения, на данный момент не разработаны. С целью стандартизации подходов к диагностике и лечению данного патологического состояния в обзоре собрана квинтэссенция современных данных о возможных факторах риска, клинических проявлениях с подробным рассмотрением патофизиологических механизмов их развития, диагностических инструментах и методах коррекции с подробным описанием показаний и сравнительной оценкой эффективности существующих методик.</p></trans-abstract><kwd-group xml:lang="en"><kwd>isthmocele</kwd><kwd>uterine scar</kwd><kwd>cesarean section</kwd><kwd>hysteroscopy</kwd><kwd>metroplasty</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>истмоцеле</kwd><kwd>рубец на матке</kwd><kwd>кесарево сечение</kwd><kwd>гистероскопия</kwd><kwd>метропластика</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Краснопольский В.И., Буянова С.Н., Щукина Н.А., Логутова Л.С. Несостоятельность шва (рубца) на матке после КС: проблемы и решения (редакционная статья). 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