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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="review-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Gynecology</journal-id><journal-title-group><journal-title xml:lang="en">Gynecology</journal-title><trans-title-group xml:lang="ru"><trans-title>Гинекология</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2079-5696</issn><issn publication-format="electronic">2079-5831</issn><publisher><publisher-name xml:lang="en">Consilium Medicum</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">629239</article-id><article-id pub-id-type="doi">10.26442/20795696.2024.4.203015</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>REVIEW</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОБЗОР</subject></subj-group><subj-group subj-group-type="article-type"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Pelvic dysfunction in women as a consequence of anatomical and functional changes of the pelvic floor during pregnancy and a reflection of adaptation to childbirth: A review</article-title><trans-title-group xml:lang="ru"><trans-title>Тазовые дисфункции у женщин как следствие анатомо-функциональных изменений тазового дна во время беременности и отражение адаптации к родам</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2837-1260</contrib-id><contrib-id contrib-id-type="scopus">55589573600</contrib-id><contrib-id contrib-id-type="spin">8739-9920</contrib-id><name-alternatives><name xml:lang="en"><surname>Bezmenko</surname><given-names>Aleksandr A.</given-names></name><name xml:lang="ru"><surname>Безменко</surname><given-names>Александр Александрович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Cand. Sci. (Med.), Assoc. Prof.</p></bio><bio xml:lang="ru"><p>канд. мед. наук, доц., врио нач. каф. и клиники акушерства и гинекологии</p></bio><email>annafrumkin@mail.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0916-4012</contrib-id><contrib-id contrib-id-type="scopus">57222085445</contrib-id><contrib-id contrib-id-type="spin">5109-0579</contrib-id><name-alternatives><name xml:lang="en"><surname>Staroverova</surname><given-names>Anna S.</given-names></name><name xml:lang="ru"><surname>Староверова</surname><given-names>Анна Сергеевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>obstetrician</p></bio><bio xml:lang="ru"><p>врач – акушер-гинеколог, зав. акушерским обсервационным отд-нием клиники акушерства и гинекологии</p></bio><email>annafrumkin@mail.ru</email><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Kirov Military Medical Academy</institution></aff><aff><institution xml:lang="ru">ФГБВОУ ВО «Военно-медицинская академия им. С.М. Кирова» Минобороны России</institution></aff><aff><institution xml:lang="kk"></institution></aff><aff><institution xml:lang="pt"></institution></aff><aff><institution xml:lang="zh"></institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Kirov Military Medical Academy</institution></aff><aff><institution xml:lang="ru">ФГБВОУ ВО «Военно-медицинская академия им. С.М. Кирова» Минобороны России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2024-12-27" publication-format="electronic"><day>27</day><month>12</month><year>2024</year></pub-date><volume>26</volume><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>326</fpage><lpage>330</lpage><history><date date-type="received" iso-8601-date="2024-03-19"><day>19</day><month>03</month><year>2024</year></date><date date-type="accepted" iso-8601-date="2024-10-14"><day>14</day><month>10</month><year>2024</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2024, Consilium Medicum</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2024, ООО "Консилиум Медикум"</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="en">Consilium Medicum</copyright-holder><copyright-holder xml:lang="ru">ООО "Консилиум Медикум"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-sa/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://gynecology.orscience.ru/2079-5831/article/view/629239">https://gynecology.orscience.ru/2079-5831/article/view/629239</self-uri><abstract xml:lang="en"><p>The review describes hormonal and biochemical changes during pregnancy that have a multifaceted effect on the structure and function of the pelvic floor and are an adaptive mechanism for stretching during the baby's passage through the birth canal. It has been shown that the onset of pelvic dysfunctions during pregnancy is a reflection of the stages of connective tissue remodeling. Pregnancy, as an additional factor affecting pelvic floor function, may be a trigger for pelvic organ prolapse. In pregnant women with insufficient adaptation of the pelvic floor, injuries during childbirth are more common, and disorders of remodeling the connective tissue components lead to pelvic organ prolapse and subsequent pelvic dysfunction. The mechanism of impaired pelvic floor connective tissue remodeling during pregnancy remains unclear and requires further research.</p></abstract><trans-abstract xml:lang="ru"><p>В обзоре раскрыты гормональные и биохимические изменения во время беременности, оказывающие многостороннее влияние на структуру и функцию тазового дна и являющиеся адаптационным механизмом к растяжению в момент прохождения ребенка по родовым путям. Показано, что дебют тазовых дисфункций во время беременности есть отражение этапов ремоделирования соединительной ткани. Беременность как дополнительный фактор, влияющий на функцию тазового дна, может быть триггерным механизмом к развитию пролапса тазовых органов. У беременных с недостаточной адаптацией тазового дна чаще случаются травмы во время родов, а нарушения процессов ремоделирования синтеза компонентов соединительной ткани приводят к пролапсу тазовых органов и тазовым дисфункциям в последующем. Механизм нарушения ремоделирования соединительной ткани тазового дна во время беременности остается не до конца ясным и требует дальнейшего изучения.</p></trans-abstract><kwd-group xml:lang="en"><kwd>remodeling</kwd><kwd>connective tissue</kwd><kwd>pelvic floor</kwd><kwd>pregnancy</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>ремоделирование</kwd><kwd>соединительная ткань</kwd><kwd>тазовое дно</kwd><kwd>беременность</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Kahyaoglu Sut H, Balkanli Kaplan P. Effect of pelvic floor muscle exercise on pelvic floor muscle activity and voiding functions during pregnancy and the postpartum period. Neurourol Urodyn. 2016;35(3):417-22. DOI:10.1002/nau.22728</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Snooks SJ, Swash M, Mathers SE, Henry MM. Effect of vaginal delivery on the pelvic floor: a 5-year follow-up. Br J Surg. 1990;77(12):1358-60. 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