GynecologyGynecology2079-56962079-5831Consilium Medicum7100310.26442/20795696.2021.2.200822Review ArticleOvarian endometriosis and fertility preservation problemChernukhaGalina E.<p>D. Sci. (Med.), Prof., Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology</p>g_chernukha@oparina4.ruDumanovskayaMadina R.<p>Cand. Sci. (Med.), Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology</p>dumanovskaya@gmail.comIlinaLilia M.<p>Cand. Sci. (Med.), Association of Gynecologists-Endocrinologists</p>bseiljina@mail.ruKulakov National Medical Research Center for Obstetrics, Gynecology and PerinatologyAssociation of Gynecologists-Endocrinologists150420212321101162505202125052021Copyright © 2021, Consilium Medicum2021<p><strong>Aim.</strong> To review the most recent literature regarding the modern management of women with ovarian endometriosis and no desire for immediate pregnancy but wanted fertility preservation in future.</p>
<p><strong>Materials and methods. </strong>The analysis of latest publications on this topic has been carried out.</p>
<p><strong>Results. </strong>Ovarian endometriosis is associated with infertility due to several factors including potential gonadotoxic effect per se and ovarian reserve decline after surgical treatment. Medical treatment is the first-line therapeutic option for patients with pelvic pain and no desire for immediate pregnancy in absence indications for the urgent surgery, for prevention disease progression. Postoperative long-term medical therapy has been effective in the prevention of endometrioma recurrence, repeated surgery, additional ovarian reserve decline and preserve fertility in future.</p>
<p><strong>Conclusion. </strong>Ovarian endometriosis management should be individualized according to the patients intentions and priorities. Long-term progestins most appropriate therapy for fertility preservation in women prior to performing surgery or provide assisted reproductive technologies, if needed.</p>endometriosisovarian endometriosisfertilitysurgeryhormonal treatmentassisted reproductive technologiesэндометриозовариальный эндометриозфертильностьхирургическое лечениегормональное лечениевспомогательные репродуктивные технологии[Chapron C, Marcellin L, Borghese B, Santulli P. Rethinking mechanisms, diagnosis and management of endometriosis. Nat Rev Endocrin. 2019; 15: 666–82. DOI: 10.1038/s41574-019-0245-z][Parasar P, Ozcan P, Terry KL. Endometriosis: Epidemiology, Diagnosis and Clinical Management. Curr Obstet Gynecol Rep. 2017; 6 (1): 34–41. DOI: 10.1007/s13669-017-0187-1][Ghiasi M, Kulkarni MT, Missmer SA. 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