GynecologyGynecology2079-56962079-5831Consilium Medicum9842310.26442/20795696.2021.6.201244Research ArticleSpontaneous pregnancy in a patient with premature ovarian failure after ovarian platelet-rich plasma injection. Case reportKraevayaElizaveta E.<p>Cand. Sci. (Med.)</p>e_kraevaya@oparina4.ruhttps://orcid.org/0000-0002-8140-0035MakarovaNatalia P.<p>D. Sci. (Biol.)</p>np_makarova@oparina4.ruBabayanAlina A.<p>Cand. Sci. (Med.)</p>a_babayan@oparina.ruKalininaElena A.<p>D. Sci. (Med.), Prof.</p>e_kalinina@oparina4.ruKulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology151220212365976002501202225012022Copyright © 2021, Consilium Medicum2021<p>The authors have described a clinical case of a spontaneous pregnancy in a patient with decreased ovarian reserve, secondary infertility and a history of an in vitro fertilization failure. Based on literature data and their own experience, the authors believe that intraovarian administration of platelet-rich plasma can increase the ovarian reserve and improve reproductive potential.</p>decreased ovarian reserveinfertilityassisted reproductive technologiesplatelet-rich plasmacase reportсниженный овариальный резервбесплодиевспомогательные репродуктивные технологииобогащенная тромбоцитами плазма[Женское бесплодие (современные подходы к диагностике и лечению. Клинические рекомендации Министерства здравоохранения РФ. 2019. Режим доступа: https://roag-portal.ru/projects_gynecology. Ссылка активна на 10.05.2021 [Zhenskoe besplodie (sovremennye podkhody k diagnostike i lecheniiu. Klinicheskie rekomendatsii Ministerstva zdravookhraneniia RF. 2019. Available at: https://roag-portal.ru/projects_gynecology. Accessed: 10.05.2021 [(in Russian)].][Tal R, Seif DB. Ovarian reserve testing: a user's guide. Am J Obstet Gynecol. 2017;217(2):129-40. 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