Follicular fluid and assisted reproductive technology programs outcomes (literature review)
| Dublin Core | PKP Metadata Items | Metadata for this Document | |
| 1. | Title | Title of document | Follicular fluid and assisted reproductive technology programs outcomes (literature review) |
| 2. | Creator | Author's name, affiliation, country | Anna G. Burduli; Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology; Russian Federation |
| 2. | Creator | Author's name, affiliation, country | Natalia A. Kitsilovskaya; Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology; Russian Federation |
| 2. | Creator | Author's name, affiliation, country | Yuliya V. Sukhova; Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology; Russian Federation |
| 2. | Creator | Author's name, affiliation, country | Irina A. Vedikhina; Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology; Russian Federation |
| 2. | Creator | Author's name, affiliation, country | Tatiana Y. Ivanets; Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology; Russian Federation |
| 2. | Creator | Author's name, affiliation, country | Vitaliy V. Chagovets; Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology; Russian Federation |
| 2. | Creator | Author's name, affiliation, country | Nataliia L. Starodubtseva; Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology; Russian Federation |
| 2. | Creator | Author's name, affiliation, country | Vladimir E. Frankevich; Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology; Russian Federation |
| 3. | Subject | Discipline(s) | |
| 3. | Subject | Keyword(s) | follicular fluid; assisted reproductive technology programs; steroid hormones; lipids; melatonin; oocytes; embryos |
| 4. | Description | Abstract | The review presents data on metabolites in the follicular fluid (FF) from the perspective of reproductive medicine and their use in order to predict outcomes of assisted reproductive technology (ART) programs. It considers various components of this biological medium (hormones, lipids, melatonin, etc.) with an assessment of their predictive value in prognosis of the effectiveness of in vitro fertilization (IVF) programs. The data on experimental directions in this field and the prospects for their use in clinical practice are presented. The article emphasizes that the growing clinical need and the unsolved problem of increasing the effectiveness of ART programs determine the need for further studies of the FF composition. Materials and methods. The review includes data related to this topic from foreign and Russian articles found in PubMed which were published in recent years. Results. Given the established fact of a direct effect of FF composition on growth and maturation of oocytes, and further, on the fertilization process, various FF metabolites are actively investigated as non-invasive markers of quality of oocytes/embryos. The article provides data on the experimental directions in this field and the prospects for their use in clinical practice. However, clinical studies of a relation between various FF metabolites levels and outcomes of IVF programs are contradictory. Conclusion. Owing large economic cost for treatment of infertility with IVF, there is need for expansion and intensification of studies to identify and use reliable predictors in prognosis of ART programs outcomes. |
| 5. | Publisher | Organizing agency, location | Consilium Medicum |
| 6. | Contributor | Sponsor(s) | The review was published within the framework of the Grant of the President of the Russian Federation for the support of young scientists MK-5090.2018.7 “The study of a hormonal profile in the blood serum and follicular fluid of patients as part of the IVF program using the enzyme immunoassay and mass spectrometry”. |
| 7. | Date | (DD-MM-YYYY) | 29.04.2020 |
| 8. | Type | Status & genre | Peer-reviewed Article |
| 8. | Type | Type | Research Article |
| 9. | Format | File format | |
| 10. | Identifier | Uniform Resource Identifier | https://gynecology.orscience.ru/2079-5831/article/view/33953 |
| 10. | Identifier | Digital Object Identifier (DOI) | 10.26442/20795696.2019.6.190663 |
| 11. | Source | Title; vol., no. (year) | Gynecology; Vol 21, No 6 (2019) |
| 12. | Language | English=en | ru |
| 13. | Relation | Supp. Files | |
| 14. | Coverage | Geo-spatial location, chronological period, research sample (gender, age, etc.) | |
| 15. | Rights | Copyright and permissions |
Copyright (c) 2019 Consilium Medicum This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License. |