Численный анализ теплообмена в тканях печени при СВЧ-абляции с использованием одной, двух, трех и четырех щелей

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Abstract

В работе рассмотрена СВЧ-терапия – популярный медицинский метод лечения патологических тканей человека, содержащих раковые опухоли. Методом конечных элементов с использованием двумерного анализа сравниваются модели коаксиальной антенны с одной, двумя, тремя и четырьмя щелями. Представленные модели основаны на волновом уравнении электромагнетизма в режиме поперечных магнитных волн в сочетании с уравнением Пеннеса в условиях переходного состояния. Кроме того, модель учитывает термоэлектрические свойства тканей человека при рабочей частоте антенны 2.45 ГГц. Представлены результаты моделирования для различных конфигураций многощелевых антенн. Проведен сравнительный конечно-элементный анализ межтканевой СВЧ-абляции в ткани печени с использованием антенн с одной, двумя, тремя и четырьмя щелями. Согласно представленным результатам, доля поврежденной ткани, подвергающейся воздействию, уменьшается за счет увеличения количества щелей. В случае четырех щелей наблюдаются сферические зоны плавления с меньшим повреждением нормальных тканей, особенно в осевом направлении.

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About the authors

E. Poorreza

Sahand University of Technology

Author for correspondence.
Email: elnaz.poorreza@gmail.com

Faculty of Electrical engineering

Iran, Islamic Republic of, Tabriz

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Supplementary files

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2. Fig. 1. Schematic diagram of a coaxial antenna inserted into biological tissue (a), its 2D model with dimensions (b), and a cross-section of the antenna with several slots (c).

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3. Fig. 2. Location of cracks and tumor.

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4. Fig. 3. Boundary conditions of the problem.

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5. Fig. 4. Calculation grid for microwave antenna.

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6. Fig. 5. Comparison of the obtained temperature distributions (1, 3) with the data [38]: 1, 2 – 7 mm; 3, 4 – 9.5 mm.

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7. Fig. 6. Total energy density absorbed in liver tissue for t = 600 s for antennas with: (a) one, (b) two, (c) three, (d) four slits.

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8. Fig. 7. Temperature distributions and corresponding three-dimensional temperature fields: (a), (d) one slit; (b), (e) two; (c), (g) three; (d), (h) four.

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9. Fig. 8. Isotherms in liver tissue in a steady state for antennas with (a) one, (b) two, (c) three, (d) four slits.

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10. Fig. 9. SA profiles for antennas with (a) one, (b) two, (c) three, (d) four slots.

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11. Fig. 10. Changes in the proportion of damage over time for antennas with (a) one, (b) two, (c) three, (d) four slots.

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12. Fig. 11. Comparison of temperature curves for positions: 1 – 5 mm, 2 – 9, 3 – 13, 4 – 17, 5 – 21, 6 – 25; for antennas with (a) one, (b) two, (c) three, (d) four slots.

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13. Fig. 12. Comparison of the dependencies of the proportion of damage for positions: 1 – 5 mm, 2 – 9, 3 – 13, 4 – 17, 5 – 21, 6 – 25; for antennas with (a) one, (b) two, (c) three, (d) four slots.

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