Scientific substantiation of the national list of chemicals affecting the endocrine system

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Abstract

Introduction. Today in the world, along with mutagens, carcinogens, reprotoxicants, chemicals that affect the endocrine system are of serious concern. Therefore, the purpose of our research was the scientific substantiation of the national list of endocrine disruptors.

Materials and methods. In order to create a national list of substances that have an effect on the endocrine system, for the selection of candidate substances, an analysis of legislation and lists of potential endocrine disruptors of the European Union, the USA, Canada, and India was made. All substances were identified by CAS numbers, areas of application and classified according to the degree of danger to the endocrine system.

Results. The draft list of endocrine disruptors circulating in the Russian Federation includes 494 chemicals used in medicine, agriculture, chemical, food, perfume and cosmetic industries. There are 19 substances in class 1A (known endocrine disruptor), 193 substances in class 1B (probable endocrine disruptor), 250 substances in class 2 (suspected endocrine disruptors), and 32 substances in class 3 (endocrine disruptors).

Conclusion. On the territory of the Russian Federation in various areas of the economy, chemicals that destroy the endocrine system are widely used. Of particular concern is the use of endocrine disruptors of hazard class 1B in perfumery, cosmetics and food products.

About the authors

Khalidya Khizbulaevna Khamidulina

Russian Register of Potentially Hazardous Chemical and Biological Substances - Branch of F.F. Erisman Federal Scientific Hygiene Center, Rospotrebnadzor; Russian Medical Academy of Continuous Professional Education, RF Ministry of Health

Author for correspondence.
Email: director@rosreg.info
ORCID iD: 0000-0001-7319-5337

Doctor of medical sciences; director of the Russian Register of Potentially Hazardous Chemical and Biological Substances — Branch of F.F. Erisman Federal Scientific Center of Hygiene, Rospotrebnadzor, 121087, Moscow, Russian Federation; Professor, Head of the Department of Hygiene, Russian Medical Academy of Continuous Professional Education, RF Ministry of Health, 125993, Moscow, Russian Federation. 

e-mail: director@rosreg.info

Russian Federation

Elena Vladimirovna Tarasova

Russian Register of Potentially Hazardous Chemical and Biological Substances - Branch of F.F. Erisman Federal Scientific Hygiene Center, Rospotrebnadzor

Email: secretary@rosreg.info
ORCID iD: 0000-0002-4020-3123

Кандидат химических наук, химик-эксперт филиала РПОХБВ ФБУН ФНЦГ им. Ф.Ф. Эрисмана Роспотребнадзора, г. Москва.

e-mail: secretary@rosreg.info

Russian Federation

Irina Valentinovna Zamkova

Russian Register of Potentially Hazardous Chemical and Biological Substances - Branch of F.F. Erisman Federal Scientific Hygiene Center, Rospotrebnadzor

Email: secretary@rosreg.info
ORCID iD: 0000-0002-7959-7246

Врач по санитарно-гигиеническим лабораторным исследованиям филиала РПОХБВ ФБУН «ФНЦГ им. Ф.Ф. Эрисмана» Роспотребнадзора, г. Москва.

e-mail: secretary@rosreg.info

Russian Federation

Ekaterina Valentinovna Dorofeeva

Russian Register of Potentially Hazardous Chemical and Biological Substances - Branch of F.F. Erisman Federal Scientific Hygiene Center, Rospotrebnadzor

Email: secretary@rosreg.info
ORCID iD: 0000-0001-8901-7914

Начальник информационно-аналитического отдела филиала РПОХБВ ФБУН «ФНЦГ им. Ф.Ф. Эрисмана» Роспотребнадзора, г. Москва.

e-mail: secretary@rosreg.info

Russian Federation

Ilgiz Nailevich Araslanov

Russian Register of Potentially Hazardous Chemical and Biological Substances - Branch of F.F. Erisman Federal Scientific Hygiene Center, Rospotrebnadzor

Email: secretary@rosreg.info
ORCID iD: 0000-0001-7694-0646

Врач по санитарно-гигиеническим лабораторным исследованиям филиала РПОХБВ ФБУН «ФНЦГ им. Ф.Ф. Эрисмана» Роспотребнадзора, г. Москва

e-mail: secretary@rosreg.info

Russian Federation

Yuliya Yurevna Aniskova

Russian Register of Potentially Hazardous Chemical and Biological Substances - Branch of F.F. Erisman Federal Scientific Hygiene Center, Rospotrebnadzor

Email: secretary@rosreg.info
ORCID iD: 0000-0002-6384-0408

Врач по санитарно-гигиеническим лабораторным исследованиям филиала РПОХБВ ФБУН «ФНЦГ им. Ф.Ф. Эрисмана» Роспотребнадзора, г. Москва

e-mail: secretary@rosreg.info

Russian Federation

Angelina Sergeevna Proskurina

Russian Register of Potentially Hazardous Chemical and Biological Substances - Branch of F.F. Erisman Federal Scientific Hygiene Center, Rospotrebnadzor; Russian Medical Academy of Continuous Professional Education, RF Ministry of Health

Email: proskurina-as@rosreg.info
ORCID iD: 0000-0003-2124-6440

Врач по санитарно-гигиеническим лабораторным исследованиям филиала РПОХБВ ФБУН «ФНЦГ им. Ф.Ф. Эрисмана» Роспотребнадзора, ассистент кафедры гигиены ФГБОУ ДПО РМАНПО Минздрава России, г. Москва.

e-mail: proskurina-as@rosreg.info

Russian Federation

Dinara Nurullaevna Rabikova

Russian Register of Potentially Hazardous Chemical and Biological Substances - Branch of F.F. Erisman Federal Scientific Hygiene Center, Rospotrebnadzor; Russian Medical Academy of Continuous Professional Education, RF Ministry of Health

Email: rabikova_dn@rosreg.info
ORCID iD: 0000-0003-3965-7600

Врач по санитарно-гигиеническим лабораторным исследованиям филиала РПОХБВ ФБУН «ФНЦГ им. Ф.Ф. Эрисмана» Роспотребнадзора, ассистент кафедры гигиены ФГБОУ ДПО РМАНПО Минздрава России.

e-mail: rabikova_dn@rosreg.info

Russian Federation

Michail Leonidovich Lastovetskiy

Russian Register of Potentially Hazardous Chemical and Biological Substances - Branch of F.F. Erisman Federal Scientific Hygiene Center, Rospotrebnadzor

Email: secretary@rosreg.info
ORCID iD: 0000-0001-9887-0626

Химик-эксперт филиала РПОХБВ ФБУН «ФНЦГ им. Ф.Ф. Эрисмана» Роспотребнадзора, г. Москва.

e-mail: secretary@rosreg.info

Russian Federation

Andrey Konstantinovich Nazarenko

Russian Register of Potentially Hazardous Chemical and Biological Substances - Branch of F.F. Erisman Federal Scientific Hygiene Center, Rospotrebnadzor

Email: secretary@rosreg.info
ORCID iD: 0000-0003-0178-4540

Химик-эксперт филиала РПОХБВ ФБУН «ФНЦГ им. Ф.Ф. Эрисмана» Роспотребнадзора, г. Москва.

e-mail: secretary@rosreg.info

Russian Federation

References

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  4. Regulation (EC) № 1272/2008 Classification, packaging and labelling of chemical substances and mixtures (CLP).
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Copyright (c) 2022 Khamidulina K.K., Tarasova E.V., Zamkova I.V., Dorofeeva E.V., Araslanov I.N., Aniskova Y.Y., Proskurina A.S., Rabikova D.N., Lastovetskiy M.L., Nazarenko A.K.



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