Factors Associated with Mortality in Patients with Coronavirus Disease (COVID-19) in Babol, North of Iran
- Авторлар: Babaei M.1, Heidari B.2, Ghorbani H.3, Ahmadnia Z.3, Rouhi S.3, Haddad Zavareh M.S.3
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Мекемелер:
- Mobility Impairment Research Center, Health Research Institute, Babol University of Medical Sciences,
- Mobility Impairment Research Center, Health Research Institute, Babol University of Medical Sciences
- Clinical Research Development Unit of Rouhani Hospital, Babol University of Medical Sciences
- Шығарылым: Том 24, № 6 (2024)
- Бөлім: Medicine
- URL: https://gynecology.orscience.ru/1871-5265/article/view/645694
- DOI: https://doi.org/10.2174/0118715265209731240129042916
- ID: 645694
Дәйексөз келтіру
Толық мәтін
Аннотация
Background:The spectrum of the clinical features of coronavirus disease 2019 (COVID-19) spans from asymptomatic or mild disease to severe respiratory failure, while different factors are related to its mortality rate. This research aimed to determine the clinical and laboratory characteristics and the associated factors of mortality in patients with COVID-19.
Background:The spectrum of the clinical features of coronavirus disease 2019 (COVID-19) spans from asymptomatic or mild disease to severe respiratory failure, while different factors are related to its mortality rate. This research aimed to determine the clinical and laboratory characteristics and the associated factors of mortality in patients with COVID-19.
Materials and Methods:Data were collected from hospitalized patients (May to June 2020), and COVID-19 was confirmed in patients by real-time polymerase chain reaction (PCR). The patient group was classified into survivor and deceased groups. The chi-square and the independent t-test with Statistical Package for the Social Sciences (SPSS) software program, version 18, were used for analysis.
Results:Mean age, hemoglobin, serum C-reactive protein (CRP), alkaline phosphatase (ALP), white blood cells, and level of procalcitonin in non-survivors were significantly higher than in survivors. Serum tumour necrosis factor-alpha (TNF-a) had a significant relationship with D-dimer (p = 0.0006). The risk of mortality in patients with serum CRP > 100 mg/dl was significantly higher than those with CRp < 000 mg/dl (odds ratio (OR) = 4.8 (95 % CI, 1.33-12.44, p = 0.01).
Conclusion:COVID-19 has different clinical features and can be an asymptomatic, mild, or severe disease. Thus, findings about the disease and the consequent outcomes differ in patients. Further studies are needed to evaluate the clinical features and consequences of COVID-19 infection.
Авторлар туралы
Mansour Babaei
Mobility Impairment Research Center, Health Research Institute, Babol University of Medical Sciences,
Email: info@benthamscience.net
Behzad Heidari
Mobility Impairment Research Center, Health Research Institute, Babol University of Medical Sciences
Email: info@benthamscience.net
Hossein Ghorbani
Clinical Research Development Unit of Rouhani Hospital, Babol University of Medical Sciences
Email: info@benthamscience.net
Zahra Ahmadnia
Clinical Research Development Unit of Rouhani Hospital, Babol University of Medical Sciences
Email: info@benthamscience.net
Samaneh Rouhi
Clinical Research Development Unit of Rouhani Hospital, Babol University of Medical Sciences
Email: info@benthamscience.net
Mahmoud Haddad Zavareh
Clinical Research Development Unit of Rouhani Hospital, Babol University of Medical Sciences
Хат алмасуға жауапты Автор.
Email: info@benthamscience.net
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