Individual Lifestyle and Male Fertility

Capa

Citar

Texto integral

Acesso aberto Acesso aberto
Acesso é fechado Acesso está concedido
Acesso é fechado Somente assinantes

Resumo

Over the past decades, there has been a significant decline in the birth rate in many countries raising the question of the role and degree of involvement of biological factors in this process. Up to 30% of couples of reproductive age have fertility problems, and in half of the cases, the cause is the male factor. However, up to 40% of cases of male infertility are idiopathic, i.e. with unexplained causes. More and more evidence suggests that environmental factors are the causes of growing male infertility and subfertility, among which the individual lifestyle seems to be the most significant. Many researchers believe that lifestyle factors make a significant contribution to the existing negative trend of global decline in male reproductive potential. The main factors of an individual lifestyle that cause a weakening of male reproductive health are considered to be obesity, nutrition, physical inactivity, smoking, excessive alcohol intake, psychological stress, low-level radio-frequency electromagnetic fields (mobile telephones and portable computers), aging and others. Many factors of an individual lifestyle can reduce the sperm production, mobility and normal morphology, increase damage to the DNA of spermatozoa, and have a negative impact on the endocrine control of reproductive function, which can lead to male subfertility and infertility. In recent years, a significant amount of data has been accumulated that allows us to create an exhaustive and multifaceted picture of the lifestyle effects on the male reproductive function. This review focuses on the negative impact of the most common factors: obesity, diet, sedentary lifestyle, smoking and alcohol consumption on spermatogenesis and the profile of reproductive hormones in men.

Sobre autores

L. Osadchuk

Federal Research Center “Institute of Cytology and Genetics”, the Siberian Branch of the RAS

Autor responsável pela correspondência
Email: losadch@bionet.nsc.ru
Russia, Novosibirsk

A. Osadchuk

Federal Research Center “Institute of Cytology and Genetics”, the Siberian Branch of the RAS

Email: losadch@bionet.nsc.ru
Russia, Novosibirsk

Bibliografia

  1. Skakkebaek N.E., Rajpert-De Meyts E., Buck Louis G.M. et al. Male reproductive disorders and fertility trends: influences of environment and genetic susceptibility // Physiol. Rev. 2016. V. 96. № 1. P. 55.
  2. Levine H., Jørgensen N., Martino–Andrade A. et al. Temporal trends in sperm count: a systematic review and meta-regression analysis // Hum. Reprod. Update. 2017. V. 23. № 6. P. 646.
  3. De Jonge C., Barratt C.L.R. The present crisis in male reproductive health: an urgent need for a political, social, and research roadmap // Andrology. 2019. V. 7. № 6. P. 762.
  4. Осадчук Л.В., Осадчук А.В. Популяционные исследования мужского репродуктивного потенциала: качество сперматозоидов как маркер репродуктивного здоровья // Урология. 2020. № 3. С. 111. Osadchuk L.V., Osadchuk A.V. [Epidemiological studies of the male reproductive potential: sperm quality as a marker of reproductive health] // Urologiia. 2020. № 3. P. 111.
  5. Aitken R.J. The changing tide of human fertility // Hum. Reprod. 2022. V. 37. № 4. P. 629.
  6. Cairo Consensus Workshop Group. The current status and future of andrology: A consensus report from the Cairo workshop group // Andrology. 2020. V. 8. № 1. P. 27.
  7. Галимова Э.Ф., Галимов Ш.Н. Мужская фертильность: модифицируемые и немодифицируемые факторы риска (обзор литературы) // Проблемы репродукции. 2015. Т. 21. № 5. С. 89. Galimova E.F., Galimov SH.N. [Male fertility: modifiable and non-modifiable risk factors (a review)] // Problemy Reproduktsii. 2015. V. 21. № 5. P. 89.
  8. Kasman A.M., Li S., Luke B. et al. Male infertility and future cardiometabolic health: does the association vary by sociodemographic factors? // Urology. 2019. V. 133. P. 121.
  9. Glazer C.H., Eisenberg M.L., Tøttenborg S.S. et al. Male factor infertility and risk of death: a nationwide record-linkage study // Hum. Reprod. 2019. V. 34. № 11. P. 2266.
  10. Alvarez S. Do some addictions interfere with fertility? // Fertil. Steril. 2015. V. 103. № 1. P. 22.
  11. Chambers T.J., Richard R.A. The impact of obesity on male fertility // Hormones (Athens) 2015. V. 14. № 4. P. 563.
  12. Durairajanayagam D. Lifestyle causes of male infertility // Arab J. Urol. 2018. V. 16. № 1. P. 10.
  13. Amiri M., Ramezani Tehrani F. Potential adverse effects of female and male obesity on fertility: a narrative review // Int. J. Endocrinol. Metab. 2020. V. 18. № 3. P. e101776.
  14. Balawender K., Orkisz S. The impact of selected modifiable lifestyle factors on male fertility in the modern world // Cent. European J. Urol. 2020. V. 73. № 4. P. 563.
  15. Benatta M., Kettache R., Buchholz N., Trinchieri A. The impact of nutrition and lifestyle on male fertility // Arch. Ital. Urol. Androl. 2020. V. 92. № 2. P. 121.
  16. Leisegang K., Sengupta P., Agarwal A., Henkel R. Obesity and male infertility: Mechanisms and management // Andrologia. 2021. V. 53. № 1. P. e13617.
  17. Nassan F.L., Chavarro J.E., Tanrikut C. Diet and men’s fertility: does diet affect sperm quality? // Fertil. Steril. 2018. V. 110. № 4. P. 570.
  18. Ramírez N., Estofán G., Tissera A. et al. Do aging, drinking, and having unhealthy weight have a synergistic impact on semen quality? // J. Assist. Reprod. Genet. 2021. V. 38. № 11. P. 2985.
  19. Hieronimus B., Ensenauer R. Influence of maternal and paternal pre-conception overweight/obesity on offspring outcomes and strategies for prevention // Eur. J. Clin. Nutr. 2021. V. 75. № 12. P. 1735.
  20. Pakpahan C., Rezano A., Margiana R. et al. The association between lipid serum and semen parameters: a systematic review // Reprod. Sci. 2022. https://doi.org/10.1007/s43032-022-01040-8
  21. Davidson L.M., Millar K., Jones C. et al. Deleterious effects of obesity upon the hormonal and molecular mechanisms controlling spermatogenesis and male fertility // Hum. Fertil. (Camb). 2015. V. 18. № 3. P. 184.
  22. Moon K.H., Park S.Y., Kim Y.W. Obesity and erectile dysfunction: from bench to clinical implication // World J. Men’s Health. 2019. V. 37. № 2. P. 138.
  23. Тимашева Я.Р., Балхиярова Ж.Р., Кочетова О.В. Современное состояние исследований в области ожирения: генетические аспекты, роль микробиома и предрасположенность к Covid-19 // Проблемы эндокринологии. 2021. Т. 67. № 4. С. 20. Timasheva Y.R., Balkhiyarova Z.R., Kochetova O.V. [Current state of the obesity research: genetic aspects, the role of microbiome, and susceptibility to Covid-19] // Problems of Endocrinology. 2021. V. 67. № 4. P. 20.
  24. Гамидов С.И., Шатылко Т.В., Гасанов Н.Г. Мужское здоровье и ожирение – диагностика и терапевтические подходы // Ожирение и метаболизм. 2019. Т. 16. № 3. С. 29. Gamidov S.I., Shatylko T.V., Gasanov N.G. [Male health and obesity – diagnostic and therapeutic approach] // Obesity and Metabolism. 2019. V. 16. № 3. P. 29.
  25. Kivimäki M., Strandberg T., Pentti J. et al. Body-mass index and risk of obesity-related complex multimorbidity: an observational multicohort study // Lancet Diabetes Endocrinol. 2022. V. 10. № 4. P. 253.
  26. Crovesy L., Rosado E.L. Interaction between genes involved in energy intake regulation and diet in obesity // Nutrition. 2019. V. 67–68. P. 110547.
  27. Liu Y., Ding Z. Obesity, a serious etiologic factor for male subfertility in modern society // Reproduction. 2017. V. 154. № 4. P. R123.
  28. Jóźków P., Rossato M. The impact of intense exercise on semen quality // Am. J. Men’s Health. 2017. V. 11. № 3. P. 654.
  29. Congdon P. Obesity and urban environments // Int. J. Environ. Res. Public Health. 2019. V. 16. № 3. P. 464.
  30. Salas-Huetos A., James E.R., Aston K.I. et al. Diet and sperm quality: Nutrients, foods and dietary patterns // Reprod. Biol. 2019. V. 19. № 3. P. 219.
  31. Sepidarkish M., Maleki-Hajiagha A., Maroufizadeh S. et al. The effect of body mass index on sperm DNA fragmentation: a systematic review and meta-analysis // Int. J. Obes. (Lond.). 2020. V. 44. № 3. P. 549.
  32. Marcho C., Oluwayiose O.A., Pilsner J.R. The preconception environment and sperm epigenetics // Andrology. 2020. V. 8. № 4. P. 924.
  33. Корнеев И.А., Мацуева И.А. Мужское бесплодие, метаболический синдром и ожирение // Урологические ведомости. 2021. Т. 11. № 2. С. 153. Korneyev I.A., Matsueva I.A. [Male infertility, metabolic syndrome and obesity] // Urology Reports (St. Petersburg). 2021. V. 11. № 2. P. 153.
  34. Guo D., Wu W., Tang Q. et al. The impact of BMI on sperm parameters and the metabolite changes of seminal plasma concomitantly // Oncotarget. 2017. V. 8. № 30. P. 48619.
  35. Wang E.Y., Huang Y., Du Q.Y. et al. Body mass index effects sperm quality: a retrospective study in Northern China // Asian J. Androl. 2017. V. 19. № 2. P. 234.
  36. Osadchuk L., Tipisova E., Kleshchev M. et al. Study of semen quality, reproductive hormone levels, and lipid levels in men from Arkhangelsk, a city in North of European Russia // Am. J. Men’s Health. 2020. V. 14. № 4. P. 1557988320939714.
  37. Осадчук Л.В., Гуторова Н.В., Людинина А.Ю. и др. Изменение гормонального и метаболического статуса у мужчин этнической группы коми с избыточной массой тела и ожирением // Ожирение и метаболизм. 2013. Т. 10. № 2. С. 28. Osadchuk L.V., Gutorova N.V., Ludinina A.Yu. et al. [Changes in hormonal and metabolic status in men of an ethnic group Komi with overweight and obesity] // Obesity and Metabolism. 2013. V. 10. № 2. Р. 28.
  38. Осадчук Л.В., Гуторова Н.В., Петрова П.Г. и др. Гормональный и метаболический статус у мужчин якутской этнической принадлежности c избыточной массой тела и ожирением // Проблемы репродукции. 2014. Т. 20. № 2. С. 78. Osadchuk L.V., Gutorova N.V., Petrova P.G. et al. [Hormonal and metabolic status in men of Yakut ethnic group with overweight and obesity] // Problemy Reproduktsii. 2014. V. 20. № 2. P. 78.
  39. Fui M.N., Dupuis P., Grossmann M. Lowered testosterone in male obesity: mechanisms, morbidity and management // Asian J. Androl. 2014. V. 16. № 2. P. 223.
  40. Grasa M.D., Gulfo J., Camps N. et al. Modulation of SHBG binding to testosterone and estradiol by sex and morbid obesity // Eur. J. Endocrinol. 2017. V. 176. № 4. P. 393.
  41. Caliber M., Saad F. Testosterone therapy for prevention and reversal of type 2 diabetes in men with low testosterone // Curr. Opin. Pharmacol. 2021. V. 58. P. 83.
  42. Ma J.X., Wang B., Li H.S. et al. Association between obesity-associated markers and semen quality parameters and serum reproductive hormones in Chinese infertile men // Reprod. Biol. Endocrinol. 2020. V. 18. № 1. P. 95.
  43. Sengupta P., Dutta S., Karkada I.R., Chinni S.V. Endocrinopathies and male infertility // Life (Basel). 2021. V. 12. № 1. P. 10.
  44. Elfassy Y., Bastard J.P., McAvoy C. et al. Adipokines in semen: physiopathology and effects on spermatozoas // Int. J. Endocrinol. 2018. V. 2018. P. 3906490.
  45. Sèdes L., Thirouard L., Maqdasy S. et al. Cholesterol: A gatekeeper of male fertility? // Front. Endocrinol. 2018. V. 9. P. 369.
  46. Liu C.Y., Chou Y.C., Lin S.H. et al. Serum lipid profiles are associated with semen quality // Asian J. Androl. 2017. V. 19. № 6. P. 633.
  47. de Neergaard R., Nielsen J.E., Jørgensen A. et al. Positive association between cholesterol in human seminal plasma and sperm counts: results from a cross-sectional cohort study and immunohistochemical investigations // Andrology. 2018. V. 6. № 6. P. 817.
  48. Deng X., Wang P., Yuan H. Epidemiology, risk factors across the spectrum of age-related metabolic diseases // J. Trace. Elem. Med. Biol. 2020. V. 61. P. 126497.
  49. McCray N.L., Young H.A., Irwig M.S. et al. The association between race, obesity, and sperm quality among men attending a university physician practice in Washington, DC // Am. J. Men’s Health. 2020. V. 14. № 3. P. 1557988320925985.
  50. Giahi L., Mohammadmoradi S., Javidan A., Sadeghi M.R. Nutritional modifications in male infertility: a systematic review covering 2 decades // Nutr. Rev. 2016. V. 74. № 2. P. 118.
  51. Gaskins A.J., Chavarro J.E. Diet and fertility: a review // Am. J. Obstet. Gynecol. 2018. V. 218. № 4. P. 379.
  52. Ilacqua A., Izzo G., Emerenziani G.P. et al. Lifestyle and fertility: the influence of stress and quality of life on male fertility // Reprod. Biol. Endocrinol. 2018. V. 16. № 1. P. 115.
  53. Ricci E., Viganò P., Cipriani S. et al. Coffee and caffeine intake and male infertility: a systematic review // Nutr. J. 2017. V. 16. № 1. P. 37.
  54. Mirnamniha M., Faroughi F., Tahmasbpour E. et al. An overview on role of some trace elements in human reproductive health, sperm function and fertilization process // Rev. Environ. Health. 2019. V. 34. № 4. P. 339.
  55. Skalny A.V., Aschner M., Tinkov A.A. Zinc // Adv. Food Nutr. Res. 2021. V. 96. P. 251.
  56. Osadchuk L., Kleshchev M., Danilenko A., Osadchuk A. Impact of seminal and serum zinc on semen quality and hormonal status: A population-based cohort study of Russian young men // J. Trace Elem. Med. Biol. 2021. V. 68. P. 126855.
  57. Осадчук Л.В., Даниленко А.Д., Осадчук А.В. Влияние цинка на мужскую фертильность // Урология. 2021. № 5. С. 84. Osadchuk L.V., Danilenko A.D., Osadchuk A.V. [An influence of zinc on male infertility] // Urologiia. 2021. № 5. P. 84.
  58. Ibañez-Perez J., Santos-Zorrozua B., Lopez-Lopez E. et al. An update on the implication of physical activity on semen quality: a systematic review and meta-analysis // Arch. Gynecol. Obstet. 2019. V. 299. № 4. P. 901.
  59. Lavín-Pérez A.M., Collado-Mateo D., Villafaina S., Calle-Guisado V. The role of exercise to reduce the impact of diabetes in the seminal quality: a systematic review // Medicina (Kaunas). 2021. V. 57. № 2. P. 159.
  60. Priskorn L., Jensen T.K., Bang A.K. et al. Is sedentary lifestyle associated with testicular function? A cross-sectional study of 1.210 men // Am. J. Epidemiol. 2016. V. 184. № 4. P. 284.
  61. Gaskins A.J., Afeiche M.C., Hauser R. et al. Paternal physical and sedentary activities in relation to semen quality and reproductive outcomes among couples from a fertility center // Hum. Reprod. 2014. V. 29. № 1. P. 2575.
  62. Hajizadeh Maleki B., Tartibian B., Chehrazi M. Effectiveness of exercise training on male factor infertility: a systematic review and network meta-analysis // Sports Health. 2022. V. 14. № 4. P. 508.
  63. Rosety M.Á., Díaz A.J., Rosety J.M. et al. Exercise improved semen quality and reproductive hormone levels in sedentary obese adults // Nutr. Hosp. 2017. V. 34. № 3. P. 608.
  64. Gerbild H., Larsen C.M., Graugaard C., Areskoug Josefsson K. Physical activity to improve erectile function: a systematic review of intervention studies // Sex. Med. 2018. V. 6. № 2. P. 75.
  65. Sansone A., Sansone M., Vaamonde D. et al. Sport, doping and male fertility // Reprod. Biol. Endocrinol. 2018. V. 16. № 1. P. 114.
  66. Zouhal H., Jayavel A., Parasuraman K. et al. Effects of exercise training on anabolic and catabolic hormones with advanced age: A systematic review // Sports Med. 2022. V. 52. № 6. P. 1353.
  67. Minas A., Fernandes A.C.C., Maciel Júnior V.L. et al. Influence of physical activity on male fertility // Andrologia. 2022. V. 54. № 7. P. e14433.
  68. Matorras R., Navarro A., Ramos D. et al. Physical activity and sperm quality: influence in sperm donors // Reprod. Biol. Endocrinol. 2022. V. 20. № 1. P. 83.
  69. Sharma R., Harlev A., Agarwal A., Esteves S.C. Cigarette smoking and semen quality: a new meta-analysis examining the effect of the 2010 World Health Organization laboratory methods for the examination of human semen // Eur. Urol. 2016. V. 70. № 4. P. 635.
  70. Аполихин О.И., Красняк С.С. Влияние алкоголя на мужскую репродуктивную систему // Общественное здоровье. 2021. Т. 1. № 2. С. 7. Apolikhin O.I., Krasnyak S.S. [The impact of alcohol on the male reproductive system] // Public Health. 2021. V. 1. № 2. P. 7.
  71. Sansone A., Di Dato C., de Angelis C. et al. Smoke, alcohol and drug addiction and male fertility // Reprod. B-iol. Endocrinol. 2018. V. 16. № 1. P. 3.
  72. Lotti F., Corona G., Vitale P. et al. Current smoking is associated with lower seminal vesicles and ejaculate volume, despite higher testosterone levels, in male subjects of infertile couples // Hum. Reprod. 2015. V. 30. № 3. P. 590.
  73. Dai J.-B., Wang Z.-X., Qiao Z.-D. The hazardous effects of tobacco smoking on male fertility // Asian J. Androl. 2015. V. 17. № 6. P. 954.
  74. Omolaoye T.S., El Shahawy O., Skosana B.T. et al. The mutagenic effect of tobacco smoke on male fertility // Environ. Sci. Pollut. Res. Int. 2021. https://doi.org/10.1007/s11356-021-16331-x
  75. Budani M.C., Fensore S., Di Marzio M., Tiboni G.M. Cigarette smoking impairs clinical outcomes of assisted reproductive technologies: A meta-analysis of the literature // Reprod. Toxicol. 2018. V. 80. P. 49.
  76. Осадчук Л.В., Попова А.В., Еркович А.А. и др. Влияние курения и алкоголя на репродуктивные и метаболические показатели молодых мужчин Западной Сибири // Урология. 2017. № 4. С. 62. Osadchuk L.V., Popova A.V., Erkovich A.A. et al. [Effects of smoking and alcohol consumption on reproductive and metabolic indicators in young men in Western Siberia] // Urologiia. 2017. № 4. P. 62.
  77. Emokpae M.A., Brown S.I. Effects of lifestyle factors on fertility: practical recommendations for modification // Reprod. Fertil. 2021. V. 2. № 1. P. R13.
  78. Gunes S., Metin Mahmutoglu A., Arslan M.A., Henkel R. Smoking-induced genetic and epigenetic alterations in infertile men // Andrologia. 2018. V. 50. № 9. P. e13124.
  79. Li X.X., Zhao Y., Huang L.X. et al. Effects of smoking and alcohol consumption on lipid profile in male adults in northwest rural China // Public Health. 2018. V. 157. P. 7.
  80. Harlev A., Agarwal A., Gunes S.O. et al. Smoking and male infertility: an evidence-based review // World J. Men’s Health. 2015. V. 33. № 3. P. 143.
  81. Jandíková H., Dušková M., Stárka L. The influence of smoking and cessation on the human reproductive hormonal balance // Physiol. Res. 2017. V. 66. Suppl 3. P. S323.
  82. Holmboe S.A., Priskorn L., Jensen T.K. et al. Use of e-cigarettes associated with lower sperm counts in a cross-sectional study of young men from the general population // Hum. Reprod. 2020. V. 35. № 7. P. 1693.
  83. Kovac J.R., Khanna A., Lipshultz L.I. The effects of cigarette smoking on male fertility // Postgrad. Med. 2015. V. 127. № 3. P. 338.
  84. Ricci E., Noli S., Ferrari S. et al. Alcohol intake and semen variables: cross-sectional analysis of a prospective cohort study of men referring to an Italian Fertility Clinic // Andrology. 2018. V. 6. № 5. P. 690.
  85. Guthauser B., Boitrelle F., Plat A. et al. Chronic excessive alcohol consumption and male fertility: a case report on reversible azoospermia and a literature review // Alcohol Alcohol. 2014. V. 49. № 1. P. 42.
  86. Jensen T.K., Swan S., Jørgensen N. et al. Alcohol and male reproductive health: a cross-sectional study of 8344 healthy men from Europe and the USA // Hum. Reprod. 2014. V. 29. № 8. P. 1801.
  87. Ricci E., Beitawi S.A., Cipriani S. et al. Semen quality and alcohol intake: a systematic review and meta-analysis // Reprod. Biomed. Online. 2017. V. 34. № 1. P. 38.

Arquivos suplementares

Arquivos suplementares
Ação
1. JATS XML
Baixar

Declaração de direitos autorais © Л.В. Осадчук, А.В. Осадчук, 2023