The method of hermetic sealing of iatrogenic damage of fetal membranes during fetal surgical interventions

Abstract

The article presents a new method for treating iatrogenic damage to membranes in fetuscopic interventions. Since surgical treatment during pregnancy is associated with the use of trocar and amniotic fetal puncture, the most frequent complication of this procedure is premature discharge of amniotic fluid and abortion (28-67%). The new method of treatment is based on the use of the technique of safe and effective hermetic sealing of fetal membranes in fetoscopy, which will reduce the frequency of iatrogenic complications. The Ministry of Health of the Russian Federation has developed a method and created the main components for hermetic sealing of membranes: a tissue sealant from the blood components of the mother - a plasma enriched with platelets, which can be injected into the area of the defect of the fetal bladder in the form of a gel and an amniotic catheter providing effective sealing of the trocar hole from the inner and outer surfaces of the membranes. We described the results of a laboratory experiment on animals, discussed the effectiveness of a new method of treatment and the possibility of its practical application.

Full Text

The article presents a new method for treating iatrogenic damage to membranes in fetuscopic interventions. Since surgical treatment during pregnancy is associated with the use of trocar and amniotic fetal puncture, the most frequent complication of this procedure is premature discharge of amniotic fluid and abortion (28-67%). The new method of treatment is based on the use of the technique of safe and effective hermetic sealing of fetal membranes in fetoscopy, which will reduce the frequency of iatrogenic complications. The Ministry of Health of the Russian Federation has developed a method and created the main components for hermetic sealing of membranes: a tissue sealant from the blood components of the mother - a plasma enriched with platelets, which can be injected into the area of the defect of the fetal bladder in the form of a gel and an amniotic catheter providing effective sealing of the trocar hole from the inner and outer surfaces of the membranes. We described the results of a laboratory experiment on animals, discussed the effectiveness of a new method of treatment and the possibility of its practical application.
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About the authors

M G Shneyderman

V.I.Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology of the Ministry of Health of the Russian Federation

Email: innamike@lmi.net
117997, Russian Federation, Moscow, ul. Akademika Oparina, d. 4

T Kh Fatkhudinov

V.I.Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology of the Ministry of Health of the Russian Federation

Email: tfat@yandex.ru
117997, Russian Federation, Moscow, ul. Akademika Oparina, d. 4

N K Tetruashvili

V.I.Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology of the Ministry of Health of the Russian Federation

Email: tetrauly@mail.ru
117997, Russian Federation, Moscow, ul. Akademika Oparina, d. 4

K V Kostyukov

V.I.Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology of the Ministry of Health of the Russian Federation

Email: kostyukov_k@yahoo.com
117997, Russian Federation, Moscow, ul. Akademika Oparina, d. 4

V A Sakalo

V.I.Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology of the Ministry of Health of the Russian Federation

Email: v_sakalo@oparina4.ru
117997, Russian Federation, Moscow, ul. Akademika Oparina, d. 4

I V Arutyunyan

V.I.Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology of the Ministry of Health of the Russian Federation

Email: tfat@yandex.ru
117997, Russian Federation, Moscow, ul. Akademika Oparina, d. 4

K A Gladkova

V.I.Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology of the Ministry of Health of the Russian Federation

Email: k_gladkova@oparina4.ru
117997, Russian Federation, Moscow, ul. Akademika Oparina, d. 4

R G Shmakov

V.I.Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology of the Ministry of Health of the Russian Federation

Email: mdshmakov@mail.ru. r_shmakov@oparina4.ru
117997, Russian Federation, Moscow, ul. Akademika Oparina, d. 4

References

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